Bianca Crifo
Overview
Explore the profile of Bianca Crifo including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
167
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0
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Recent Articles
1.
Kennedy C, Doyle R, Gough O, Mcevoy C, Anallen S, McAnallen S, et al.
Kidney360
. 2024 Oct;
5(12):1799-1812.
PMID: 39450948
No abstract available.
2.
Saesen R, Machado M, Crifo B, Liu L, de Vries C, Herold R, et al.
Front Med (Lausanne)
. 2023 Jun;
10:1181702.
PMID: 37324145
Background: The European Medicines Agency (EMA) interacts with many different stakeholders involved in the development of drugs, including academic researchers. In recent years, EMA has collaborated more closely with academia,...
3.
Crifo B, MacNaughton W
Am J Physiol Gastrointest Liver Physiol
. 2021 Dec;
322(1):G169-G182.
PMID: 34878937
Mucosal and histological healing have become the gold standards for assessing the efficacy of therapy in patients living with inflammatory bowel diseases (IBD). Despite these being the accepted goals in...
4.
Criscuoli M, Ulivieri C, Filippi I, Monaci S, Guerrini G, Crifo B, et al.
J Cell Physiol
. 2020 Jan;
235(11):8058-8070.
PMID: 31944299
Hypoxia occurs in physiological and pathological conditions. T cells experience hypoxia in pathological and physiological conditions as well as in lymphoid organs. Indeed, hypoxia-inducible factor 1α (HIF-1α) affects T cell...
5.
Schaible B, Crifo B, Schaffer K, Taylor C
J Biol Chem
. 2019 Dec;
295(5):1195-1201.
PMID: 31826919
is an extracellular opportunistic bacterial pathogen commonly associated with infectious complications in susceptible individuals, such as those with underlying diseases including HIV/AIDS and cystic fibrosis. Antibiotic resistance in multiple strains...
6.
Crifo B, Schaible B, Brown E, Halligan D, Scholz C, Fitzpatrick S, et al.
J Immunol
. 2019 Feb;
202(5):1521-1530.
PMID: 30700584
Hypoxia is a common and prominent feature of the microenvironment at sites of bacteria-associated inflammation in inflammatory bowel disease. The prolyl-hydroxylases (PHD1/2/3) and the asparaginyl-hydroxylase factor-inhibiting HIF are oxygen-sensing enzymes...
7.
Hickey C, Schaible B, Nguyen S, Hurley D, Srikumar S, Fanning S, et al.
Front Cell Infect Microbiol
. 2018 Nov;
8:357.
PMID: 30416988
The factors influencing the virulence of in the development of invasive infection remain poorly understood. Here, we investigated the role of the host microenvironment in shaping pathogen virulence and investigated...
8.
Manresa M, Smith L, Casals-Diaz L, Fagundes R, Brown E, Radhakrishnan P, et al.
Allergy
. 2018 Nov;
74(4):753-766.
PMID: 30394557
Background: When an immune cell migrates from the bloodstream to a site of chronic inflammation, it experiences a profound decrease in microenvironmental oxygen levels leading to a state of cellular...
9.
Cavadas M, Mesnieres M, Crifo B, Manresa M, Selfridge A, Keogh C, et al.
Sci Rep
. 2016 Aug;
6:31355.
PMID: 27531581
Cellular exposure to hypoxia results in altered gene expression in a range of physiologic and pathophysiologic states. Discrete cohorts of genes can be either up- or down-regulated in response to...
10.
Scholz C, Rodriguez J, Pickel C, Burr S, Fabrizio J, Nolan K, et al.
PLoS Biol
. 2016 Jan;
14(1):e1002347.
PMID: 26752685
The asparagine hydroxylase, factor inhibiting HIF (FIH), confers oxygen-dependence upon the hypoxia-inducible factor (HIF), a master regulator of the cellular adaptive response to hypoxia. Studies investigating whether asparagine hydroxylation is...