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Bertrand Brassart

Explore the profile of Bertrand Brassart including associated specialties, affiliations and a list of published articles. Areas
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Articles 34
Citations 646
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Recent Articles
1.
Nannan L, Decombis S, Terryn C, Audonnet S, Michel J, Brassart-Pasco S, et al.
J Extracell Biol . 2024 Jun; 3(3):e145. PMID: 38939412
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy with poor prognosis due to its highly metastatic profile. Intercellular communication between cancer and stromal cells via extracellular vesicles (EVs) is crucial...
2.
Nannan L, Gsell W, Belderbos S, Gallet C, Wouters J, Brassart-Pasco S, et al.
Br J Cancer . 2023 Mar; 128(11):2000-2012. PMID: 37002342
Background: Pancreatic ductal adenocarcinoma (PDAC) is highly malignant with a very poor prognosis due to its silent development and metastatic profile with a 5-year survival rate below 10%. PDAC is...
3.
Oudart J, Villemin M, Brassart B, Sellier C, Terryn C, Dupont-Deshorgue A, et al.
Cell Adh Migr . 2021 Jul; 15(1):215-223. PMID: 34308743
We previously demonstrated that F4 peptide (CNPEDCLYPVSHAHQR) from collagen XIX was able to inhibit melanoma cell migration and cancer progression in a mouse melanoma model. The aim of the present...
4.
Bretaudeau C, Baud S, Dupont-Deshorgue A, Cousin R, Brassart B, Brassart-Pasco S
Biomolecules . 2021 Jan; 11(1). PMID: 33396696
Oral tongue squamous cell carcinoma is one of the most prevalent head and neck cancers. During tumor progression, elastin fragments are released in the tumor microenvironment. Among them, we previously...
5.
Nannan L, Oudart J, Monboisse J, Ramont L, Brassart-Pasco S, Brassart B
Front Oncol . 2020 Sep; 10:1456. PMID: 32974169
Extracellular vesicles (EVs) like exosomes and shed microvesicles are generated by many different cells. However, among all the cells, cancer cells are now recognized to secrete more EVs than healthy...
6.
Vautrin-Glabik A, Devy J, Bour C, Baud S, Choulier L, Hoarau A, et al.
Front Cell Dev Biol . 2020 Aug; 8:775. PMID: 32850867
Angiogenesis is defined as the formation of new capillaries by sprouting from the pre-existing microvasculature. It occurs in physiological and pathological processes particularly in tumor growth and metastasis. α1, α2,...
7.
Lefebvre T, Rybarczyk P, Bretaudeau C, Vanlaeys A, Cousin R, Brassart-Pasco S, et al.
Front Cell Dev Biol . 2020 Aug; 8:549. PMID: 32733880
Pancreatic ductal adenocarcinoma (PDAC) is a malignancy with a very poor prognosis due to highly metastatic profile. Cell migration is an essential step of the metastatic cascade allowing cancer cells...
8.
Brassart-Pasco S, Dalstein V, Brassart B, Dewolf M, Clavel C, Oudart J
Pharmacogenomics . 2020 Jun; 21(10):705-720. PMID: 32567537
Immunotherapies are now considered as a pillar of non-small-cell lung cancer treatment. The main targets of immune-checkpoint inhibitors (ICI) are programmed cell death 1/programmed cell death ligand 1 and cytotoxic...
9.
Brassart-Pasco S, Brezillon S, Brassart B, Ramont L, Oudart J, Monboisse J
Front Oncol . 2020 May; 10:397. PMID: 32351878
The tumor microenvironment (TME) is composed of various cell types embedded in an altered extracellular matrix (ECM). ECM not only serves as a support for tumor cell but also regulates...
10.
Vanlaeys A, Fouquet G, Kischel P, Hague F, Pasco-Brassart S, Lefebvre T, et al.
Arch Toxicol . 2020 Feb; 94(3):735-747. PMID: 32080757
Cadmium is a xenobiotic involved in neoplastic transformation. Cadmium enters the cells through divalent cation transporters including the Transient Receptor Potential Melastatin-related 7 (TRPM7) which is known to be involved...