Bernard Renaux
Overview
Explore the profile of Bernard Renaux including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
310
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Recent Articles
1.
Peplowski M, Dicay M, Baggio C, Wysokinski F, Renaux B, Hollenberg M, et al.
J Mol Med (Berl)
. 2018 Aug;
96(10):1081-1093.
PMID: 30090948
Key Messages: • IFNγ suppresses the expression of AQP3 in intestinal epithelial cells. • Proximal AQP3 promoter elements are sufficient to drive constitutive expression and mediate the IFNγ-induced downregulation of...
2.
Peplowski M, Vegso A, Iablokov V, Dicay M, Zaheer R, Renaux B, et al.
Physiol Rep
. 2017 Oct;
5(19).
PMID: 29038361
Inflammatory diseases of the gut are associated with altered electrolyte and water transport, leading to the development of diarrhea. Epithelially expressed aquaporins (AQPs) are downregulated in inflammation, although the mechanisms...
3.
Gillrie M, Renaux B, Russell-Goldman E, Avril M, Brazier A, Mihara K, et al.
mBio
. 2016 Sep;
7(5).
PMID: 27624125
Unlabelled: Plasmodium falciparum malaria remains one of the most deadly infections worldwide. The pathogenesis of the infection results from the sequestration of infected erythrocytes (IRBC) in vital organs, including the...
4.
Mihara K, Ramachandran R, Saifeddine M, Hansen K, Renaux B, Polley D, et al.
Mol Pharmacol
. 2016 Mar;
89(5):606-14.
PMID: 26957205
Thrombin is known to signal to cells by cleaving/activating a G-protein-coupled family of proteinase-activated receptors (PARs). The signaling mechanism involves the proteolytic unmasking of an N-terminal receptor sequence that acts...
5.
Allan E, Tailor P, Balce D, Pirzadeh P, McKenna N, Renaux B, et al.
J Immunol
. 2014 Apr;
192(11):4989-5001.
PMID: 24778444
The chemistries within phagosomes of APCs mediate microbial destruction as well as generate peptides for presentation on MHC class II. The antimicrobial effector NADPH oxidase (NOX2), which generates superoxide within...
6.
Sharma N, Fahr J, Renaux B, Saifeddine M, Kumar R, Nishikawa S, et al.
Biochem Cell Biol
. 2013 Nov;
91(6):487-97.
PMID: 24219291
Implantation serine proteinase 2 (ISP2), a S1 family serine proteinase, is known for its role in the critical processes of embryo hatching and implantation in the mouse uterus. Native implantation...
7.
Mihara K, Ramachandran R, Renaux B, Saifeddine M, Hollenberg M
J Biol Chem
. 2013 Sep;
288(46):32979-90.
PMID: 24052258
Neutrophil proteinases released at sites of inflammation can affect tissue function by either activating or disarming signal transduction mediated by proteinase-activated receptors (PARs). Because PAR1 is expressed at sites where...
8.
Hirota C, Moreau F, Iablokov V, Dicay M, Renaux B, Hollenberg M, et al.
Am J Physiol Gastrointest Liver Physiol
. 2012 Apr;
303(1):G111-9.
PMID: 22517768
Proteinase-activated receptor (PAR)(2), a G protein-coupled receptor activated by serine proteinases, has been implicated in both intestinal inflammation and epithelial proliferation. Cyclooxygenase (COX)-2 is overexpressed in the gut during inflammation...
9.
Ramachandran R, Eissa A, Mihara K, Oikonomopoulou K, Saifeddine M, Renaux B, et al.
Biol Chem
. 2012 Apr;
393(5):421-7.
PMID: 22505524
We compared signalling pathways such as calcium transients, MAPK activation, β-arrestin interactions and receptor internalization triggered by kallikrein-related peptidases (KLKs) 8 and 14 in human and rat proteinase-activated receptor (PAR)2-expressing...
10.
Sharma N, Kumar R, Renaux B, Saifeddine M, Nishikawa S, Mihara K, et al.
PLoS One
. 2011 Dec;
6(11):e27888.
PMID: 22132161
Implantation S1 family serine proteinases (ISPs) are tryptases involved in embryo hatching and uterine implantation in the mouse. The two different ISP proteins (ISP1 and ISP2) have been detected in...