Bernard D Santarsiero
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Explore the profile of Bernard D Santarsiero including associated specialties, affiliations and a list of published articles.
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64
Citations
1443
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Recent Articles
1.
Alqarni S, Cooper L, Achi J, Bott R, Sali V, Brown A, et al.
J Med Chem
. 2022 Oct;
65(20):14104-14120.
PMID: 36260129
The influenza A virus (IAV) is a highly contagious virus that causes pandemics and seasonal epidemics, which are major public health issues. Current anti-influenza therapeutics are limited partly due to...
2.
Heinz-Kunert S, Pandya A, Thuc Dang V, Tran P, Ghosh S, McElheny D, et al.
J Am Chem Soc
. 2022 Apr;
144(15):7001-7009.
PMID: 35390261
The evolution of proteins from simpler, self-assembled peptides provides a powerful blueprint for the design of complex synthetic materials. Previously, peptide-metal frameworks using short sequences (≤3 residues) have shown great...
3.
Argade M, Straub C, Rusali L, Santarsiero B, Riley A
Org Lett
. 2021 Jul;
23(20):7693-7697.
PMID: 34292752
The first synthesis of aristoquinoline (), a naturally occurring nicotinic acetylcholine receptor (nAChR) antagonist, was accomplished using two different approaches. Comparison of the synthetic material's spectroscopic data to that of...
4.
Ghosh D, Sinhababu S, Santarsiero B, Mankad N
J Am Chem Soc
. 2020 Jun;
142(29):12635-12642.
PMID: 32598845
Constructing synthetic models of the Mo/Cu active site of aerobic carbon monoxide dehydrogenase (CODH) has been a long-standing synthetic challenge thought to be crucial for understanding how atmospheric concentrations of...
5.
Zhou B, Shetye G, Yu Y, Santarsiero B, Klein L, Abad-Zapatero C, et al.
J Nat Prod
. 2020 Feb;
83(3):657-667.
PMID: 32031795
This study represents a systematic chemical and biological study of the rufomycin (RUF) class of cyclic heptapeptides, which our anti-TB drug discovery efforts have identified as potentially promising anti-TB agents...
6.
Wolf N, Lee H, Choules M, Pauli G, Phansalkar R, Anderson J, et al.
ACS Infect Dis
. 2019 Apr;
5(6):829-840.
PMID: 30990022
Addressing the urgent need to develop novel drugs against drug-resistant Mycobacterium tuberculosis ( M. tb) strains, ecumicin (ECU) and rufomycin I (RUFI) are being explored as promising new leads targeting...
7.
Waldhart G, Mankad N, Santarsiero B
Org Lett
. 2018 May;
20(12):3714.
PMID: 29798676
No abstract available.
8.
Hevener K, Santarsiero B, Lee H, Jones J, Boci T, Johnson M, et al.
Acta Crystallogr F Struct Biol Commun
. 2018 Feb;
74(Pt 2):105-112.
PMID: 29400320
Enoyl-acyl carrier protein (ACP) reductase II (FabK) is a critical rate-limiting enzyme in the bacterial type II fatty-acid synthesis (FAS II) pathway. FAS II pathway enzymes are markedly disparate from...
9.
May D, Kang H, Santarsiero B, Krunic A, Shen Q, Burdette J, et al.
J Nat Prod
. 2018 Jan;
81(3):572-578.
PMID: 29381355
The cell extracts of two cultured freshwater Nostoc spp., UIC 10279 and UIC 10366, both from the suburbs of Chicago, showed antiproliferative activity against MDA-MB-231 and MDA-MB-435 cancer cell lines....
10.
Santarsiero B
Acta Crystallogr C Struct Chem
. 2017 Dec;
73(Pt 12):1038-1039.
PMID: 29206112
No abstract available.