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Benno Kusters

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Articles 121
Citations 2377
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Recent Articles
11.
Miltenburg J, Gorissen M, van Outersterp I, Versteeg I, Nowak A, Rodenburg R, et al.
Int J Mol Sci . 2024 Jul; 25(13). PMID: 39000369
Phaeochromocytomas and paragangliomas (PPGLs) are rare neuroendocrine tumours arising from chromaffin cells. Pathogenic variants in the gene are associated with malignancy and poor prognosis. When metastases arise, limited treatment options...
12.
Jakel L, de Kort A, Stellingwerf A, Hernandez Utrilla C, Kersten I, Vervuurt M, et al.
Acta Neuropathol Commun . 2024 Jun; 12(1):103. PMID: 38915119
Cerebral amyloid angiopathy (CAA) is a highly prevalent and progressive pathology, involving amyloid-β (Aβ) deposition in the cerebral blood vessel walls. CAA is associated with an increased risk for intracerebral...
13.
Moller B, Becker L, Saffari A, Afenjar A, Coci E, Williamson R, et al.
Brain . 2024 Jun; 148(2):597-612. PMID: 38848546
Intracellular trafficking involves an intricate machinery of motor complexes, including the dynein complex, to shuttle cargo for autophagolysosomal degradation. Deficiency in dynein axonemal chains, as well as cytoplasmic light and...
14.
Jakel L, Claassen K, de Kort A, Jolink W, Vermeiren Y, Schreuder F, et al.
Brain Pathol . 2024 May; 34(6):e13270. PMID: 38763889
Decreased microvascular levels of claudin-5 in the occipital and temporal lobe of patients with cerebral amyloid angiopathy are associated with intracerebral haemorrhage.
15.
Verhoeven J, Kramer J, Seeger J, Molenaar J, Braakman H, Kamsteeg E, et al.
Neurology . 2024 Feb; 102(5):e209164. PMID: 38373275
Brody disease is a rare autosomal recessive myopathy, caused by pathogenic variants in the gene. It is characterized by an exercise-induced delay in muscle relaxation, often reported as muscle stiffness....
16.
Hubregtse L, Bouman K, Lama C, Lassche S, de Graaf N, Taglietti V, et al.
Neuromuscul Disord . 2024 Feb; 36:6-15. PMID: 38306719
The aim of this study was to identify key routinely used myopathologic biomarkers of FSHD1. Needle muscle biopsies were taken in 34 affected muscles (m. quadriceps femoris (QF), n =...
17.
de Winter J, Molenaar J, Yuen M, van der Pijl R, Shen S, Conijn S, et al.
J Clin Invest . 2024 Feb; 134(3). PMID: 38299595
No abstract available.
18.
Spiekman I, Geurts B, Zeverijn L, de Wit G, van der Noort V, Roepman P, et al.
Oncologist . 2023 Dec; 29(5):431-440. PMID: 38109296
Background: The prognosis of malignant primary high-grade brain tumors, predominantly glioblastomas, is poor despite intensive multimodality treatment options. In more than 50% of patients with glioblastomas, potentially targetable mutations are...
19.
van Ede E, Hoeks M, Hofland J, Linssen V, van Kuppevelt T, Versteeg E, et al.
BMC Anesthesiol . 2023 Jun; 23(1):217. PMID: 37344791
Background: Non-AT-III mediated heparin-resistance during CPB occurs by complex-forming with heparin-binding proteins. Currently, there are no specific recommendations for non-AT-III mediated heparin-resistance. Case Presentation: We present a fatal case of...
20.
Claus C, Slavin M, Ansseau E, Lancelot C, Bah K, Lassche S, et al.
Skelet Muscle . 2023 Mar; 13(1):5. PMID: 36882853
Background: We have previously demonstrated that double homeobox 4 centromeric (DUX4C) encoded for a functional DUX4c protein upregulated in dystrophic skeletal muscles. Based on gain- and loss-of-function studies we have...