Benjamin R Sabari
Overview
Explore the profile of Benjamin R Sabari including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
25
Citations
4570
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Ahn J, Guo Y, Lyons H, Mackintosh S, Lau B, Edmondson R, et al.
Mol Cell
. 2025 Feb;
85(4):708-725.e9.
PMID: 39922194
Recurrent cancer-causing fusions of NUP98 produce higher-order assemblies known as condensates. How NUP98 oncofusion-driven condensates activate oncogenes remains poorly understood. Here, we investigate NUP98-PHF23, a leukemogenic chimera of the disordered...
2.
Vashishtha S, Sabari B
J Mol Biol
. 2025 Jan;
437(5):168953.
PMID: 39826710
Disordered regions of proteins play crucial roles in cellular functions through diverse mechanisms. Some disordered regions function by promoting the formation of biomolecular condensates through dynamic multivalent interactions. While many...
3.
Pei G, Lyons H, Li P, Sabari B
Nat Rev Mol Cell Biol
. 2024 Nov;
26(3):213-236.
PMID: 39516712
Biomolecular condensates regulate transcription by dynamically compartmentalizing the transcription machinery. Classic models of transcription regulation focus on the recruitment and regulation of RNA polymerase II by the formation of complexes...
4.
Sabari B, Hyman A, Hnisz D
Nat Rev Genet
. 2024 Oct;
PMID: 39433596
Biomolecular condensates are thought to create subcellular microenvironments that regulate specific biochemical activities. Extensive in vitro work has helped link condensate formation to a wide range of cellular processes, including...
5.
De La Cruz N, Pradhan P, Veettil R, Conti B, Oppikofer M, Sabari B
Mol Cell
. 2024 Sep;
84(18):3497-3512.e9.
PMID: 39232584
Selective compartmentalization of cellular contents is fundamental to the regulation of biochemistry. Although membrane-bound organelles control composition by using a semi-permeable barrier, biomolecular condensates rely on interactions among constituents to...
6.
Gan P, Eppert M, De La Cruz N, Lyons H, Shah A, Veettil R, et al.
Sci Adv
. 2024 Mar;
10(11):eadk7160.
PMID: 38489358
During development, cells make switch-like decisions to activate new gene programs specifying cell lineage. The mechanisms underlying these decisive choices remain unclear. Here, we show that the cardiovascular transcriptional coactivator...
7.
Chi P, Lewis P, Lu C, Lu J, Ruthenburg A, Sabari B, et al.
Nat Genet
. 2023 Feb;
55(4):522-523.
PMID: 36849658
No abstract available.
8.
Boeynaems S, Chong S, Gsponer J, Holt L, Milovanovic D, Mitrea D, et al.
J Mol Biol
. 2023 Jan;
435(5):167971.
PMID: 36690068
In the past almost 15 years, we witnessed the birth of a new scientific field focused on the existence, formation, biological functions, and disease associations of membraneless bodies in cells,...
9.
Lyons H, Veettil R, Pradhan P, Fornero C, De La Cruz N, Ito K, et al.
Cell
. 2023 Jan;
186(2):327-345.e28.
PMID: 36603581
Components of transcriptional machinery are selectively partitioned into specific condensates, often mediated by protein disorder, yet we know little about how this specificity is achieved. Here, we show that condensates...
10.
Eppert M, Sabari B
Mol Cell
. 2022 Nov;
82(21):3965-3967.
PMID: 36332603
In this issue of Molecular Cell, Song et al. demonstrate that mutations to the YEATS domain of ENL aberrantly activate gene expression by forming condensates on specific genomic loci. By...