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Benjamin R Capraro

Explore the profile of Benjamin R Capraro including associated specialties, affiliations and a list of published articles. Areas
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Articles 12
Citations 517
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Recent Articles
1.
He K, Song E, Upadhyayula S, Dang S, Gaudin R, Skillern W, et al.
J Cell Biol . 2020 Jan; 219(3). PMID: 31962345
Clathrin-coated vesicles lose their clathrin lattice within seconds of pinching off, through the action of the Hsc70 "uncoating ATPase." The J- and PTEN-like domain-containing proteins, auxilin 1 (Aux1) and auxilin...
2.
Bocking T, Upadhyayula S, Rapoport I, Capraro B, Kirchhausen T
Methods Mol Biol . 2018 Aug; 1847:121-146. PMID: 30129014
The disassembly of the clathrin lattice surrounding coated vesicles is the obligatory last step in their life cycle. It is mediated by the coordinated recruitment of auxilin and Hsc70, an...
3.
He K, Iii R, Upadhyayula S, Song E, Dang S, Capraro B, et al.
Nature . 2017 Dec; 552(7685):410-414. PMID: 29236694
Vesicular carriers transport proteins and lipids from one organelle to another, recognizing specific identifiers for the donor and acceptor membranes. Two important identifiers are phosphoinositides and GTP-bound GTPases, which provide...
4.
Chen Z, Chang K, Capraro B, Zhu C, Hsu C, Baumgart T
J Am Chem Soc . 2014 Feb; 136(12):4557-64. PMID: 24568626
Endophilin A1 is a homodimeric membrane-binding endocytic accessory protein with a high dimerization affinity. Its function has been hypothesized to involve autoinhibition. However, the autoinhibition mechanism, as well as the...
5.
Zhao Y, Liu J, Yang C, Capraro B, Baumgart T, Bradley R, et al.
Dev Cell . 2013 Aug; 26(3):266-78. PMID: 23948253
Dynamic shape changes of the plasma membrane are fundamental to many processes, ranging from morphogenesis and cell migration to phagocytosis and viral propagation. Here, we demonstrate that Exo70, a component...
6.
Heinrich M, Capraro B, Tian A, Isas J, Langen R, Baumgart T
J Phys Chem Lett . 2013 Jun; 1(23):3401-3406. PMID: 23772271
Biological membrane functions are coupled to membrane curvature, the regulation of which often involves membrane-associated proteins. The membrane-binding N-terminal amphipathic helix-containing BIN/Amphiphysin/Rvs (N-BAR) domain of amphiphysin is implicated in curvature...
7.
Capraro B, Shi Z, Wu T, Chen Z, Dunn J, Rhoades E, et al.
J Biol Chem . 2013 Mar; 288(18):12533-43. PMID: 23482561
The recruitment to plasma membrane invaginations of the protein endophilin is a temporally regulated step in clathrin-mediated endocytosis. Endophilin is believed to sense or stabilize membrane curvature, which in turn...
8.
Hsieh W, Hsu C, Capraro B, Wu T, Chen C, Yang S, et al.
Langmuir . 2012 Aug; 28(35):12838-43. PMID: 22881196
Cellular membrane deformation and the associated redistribution of membrane-bound proteins are important aspects of membrane function. Current model membrane approaches for studying curvature sensing are limited to positive curvatures and...
9.
Baumgart T, Capraro B, Zhu C, Das S
Annu Rev Phys Chem . 2011 Jan; 62:483-506. PMID: 21219150
Research investigating lipid membrane curvature generation and sensing is a rapidly developing frontier in membrane physical chemistry and biophysics. The fast recent progress is based on the discovery of a...
10.
Capraro B, Yoon Y, Cho W, Baumgart T
J Am Chem Soc . 2010 Jan; 132(4):1200-1. PMID: 20050657
The protein epsin is believed to play important roles in clathrin-mediated endocytosis, including generation of the high membrane curvature necessary for vesicle formation. Here we assess the basis for this...