Benjamin Perry
Overview
Explore the profile of Benjamin Perry including associated specialties, affiliations and a list of published articles.
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Articles
29
Citations
254
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Recent Articles
1.
Kim K, Comber J, Pursel A, Hobby G, McCormick C, Fisher M, et al.
Org Biomol Chem
. 2024 May;
22(24):4940-4949.
PMID: 38809109
The synthesis of a biologically relevant 2-amino-3-alkylamido 4-quinazolinone has been accomplished in four steps from commercially available materials using design principles from both modular and divergent synthesis. 3-Alkylation of 2-chloro-4(3)-quinazolinone...
2.
Klug D, Tse E, Silva D, Cao Y, Charman S, Chauhan J, et al.
ACS Infect Dis
. 2023 Nov;
9(12):2423-2435.
PMID: 37991879
Antimicrobial resistance (AMR) is widely acknowledged as one of the most serious public health threats facing the world, yet the private sector finds it challenging to generate much-needed medicines. As...
3.
Boby M, Fearon D, Ferla M, Filep M, Koekemoer L, Robinson M, et al.
Science
. 2023 Nov;
382(6671):eabo7201.
PMID: 37943932
We report the results of the COVID Moonshot, a fully open-science, crowdsourced, and structure-enabled drug discovery campaign targeting the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease. We discovered...
4.
Dichiara M, Simpson Q, Quotadamo A, Jalani H, Huang A, Millard C, et al.
ACS Infect Dis
. 2023 Jul;
9(8):1470-1487.
PMID: 37417544
Leishmaniasis is a collection of diseases caused by more than 20 parasite species that manifest as either visceral, cutaneous, or mucocutaneous leishmaniasis. Despite the significant mortality and morbidity associated with...
5.
Roy S, Wang D, Rudzite A, Perry B, Scalabrino M, Thapa M, et al.
Cell Rep Methods
. 2023 May;
3(4):100453.
PMID: 37159670
Visual processing in the retina depends on the collective activity of large ensembles of neurons organized in different layers. Current techniques for measuring activity of layer-specific neural ensembles rely on...
6.
Tawaraishi T, Ochida A, Akao Y, Itono S, Kamaura M, Akther T, et al.
J Med Chem
. 2023 Jan;
66(2):1221-1238.
PMID: 36607408
Probing multiple proprietary pharmaceutical libraries in parallel via virtual screening allowed rapid expansion of the structure-activity relationship (SAR) around hit compounds with moderate efficacy against , the causative agent of...
7.
Kuzuki T, Perry B, Mowbray C
Yakugaku Zasshi
. 2022 Jul;
142(7):685-689.
PMID: 35781494
The Neglected Tropical Disease (NTD) Drug Discovery Booster is a collaborative project in early small molecule drug discovery running since 2015 between Drugs for Neglected Diseases initiative (DNDi) and pharmaceutical...
8.
Samby K, Besson D, Dutta A, Patra B, Doy A, Glossop P, et al.
ACS Infect Dis
. 2022 Mar;
8(4):713-720.
PMID: 35286809
The current Covid-19 pandemic has underlined the need for a more coordinated and forward-looking investment in the search for new medicines targeting emerging health care threats. Repositioning currently approved drugs...
9.
Lim W, Nyuykonge B, Eadie K, Konings M, Smeets J, Fahal A, et al.
PLoS Negl Trop Dis
. 2022 Feb;
16(2):e0010159.
PMID: 35120131
Eumycetoma is a chronic subcutaneous neglected tropical disease that can be caused by more than 40 different fungal causative agents. The most common causative agents produce black grains and belong...
10.
Akao Y, Canan S, Cao Y, Condroski K, Engkvist O, Itono S, et al.
RSC Med Chem
. 2021 May;
12(3):384-393.
PMID: 34041487
An innovative pre-competitive virtual screening collaboration was engaged to validate and subsequently explore an imidazo[1,2-]pyridine screening hit for visceral leishmaniasis. probing of five proprietary pharmaceutical company libraries enabled rapid expansion...