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Benjamin Lacroix

Explore the profile of Benjamin Lacroix including associated specialties, affiliations and a list of published articles. Areas
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Articles 27
Citations 857
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Recent Articles
1.
Roumbo L, Ossareh-Nazari B, Vigneron S, Stefani I, Van Hove L, Legros V, et al.
EMBO J . 2025 Feb; PMID: 39962268
MAST-like, or Greatwall (Gwl), an atypical protein kinase related to the evolutionarily conserved MAST kinase family, is crucial for cell cycle control during mitotic entry. Mechanistically, Greatwall is activated by...
2.
Xie J, Najafi J, Nommick A, Lederer L, Salle J, Dmitrieff S, et al.
Curr Biol . 2025 Jan; 35(2):413-421.e6. PMID: 39755120
The regulation of mitotic spindle positioning and orientation is central to the morphogenesis of developing embryos and tissues. In many multicellular contexts, cell geometry has been shown to have a...
3.
Connors C, Mauro M, Wiles J, Countryman A, Martin S, Lacroix B, et al.
Mol Biol Cell . 2024 May; 35(7):ar94. PMID: 38696255
Animal cell cytokinesis, or the physical division of one cell into two, is thought to be driven by constriction of an actomyosin contractile ring at the division plane. The mechanisms...
4.
Chenevert J, Robert M, Salle J, Cacchia S, Lorca T, Castro A, et al.
Methods Mol Biol . 2024 Feb; 2740:187-210. PMID: 38393477
During eukaryotic cell division a microtubule-based structure, the mitotic spindle, aligns and segregates chromosomes between daughter cells. Understanding how this cellular structure is assembled and coordinated in space and in...
5.
Lacroix B, Vigneron S, Labbe J, Pintard L, Lionne C, Labesse G, et al.
EMBO J . 2024 Feb; 43(6):993-1014. PMID: 38378890
Entry into mitosis has been classically attributed to the activation of a cyclin B/Cdk1 amplification loop via a partial pool of this kinase becoming active at the end of G2...
6.
Connors C, Mauro M, Wiles J, Countryman A, Martin S, Lacroix B, et al.
bioRxiv . 2023 Nov; PMID: 38014027
Animal cell cytokinesis, or the physical division of one cell into two, is thought to be driven by constriction of an actomyosin contractile ring at the division plane. The mechanisms...
7.
Macaisne N, Bellutti L, Laband K, Edwards F, Pitayu-Nugroho L, Gervais A, et al.
Elife . 2023 Feb; 12. PMID: 36799894
During cell division, chromosome segregation is orchestrated by a microtubule-based spindle. Interaction between spindle microtubules and kinetochores is central to the bi-orientation of chromosomes. Initially dynamic to allow spindle assembly...
8.
Lacroix B, Lorca T, Castro A
Front Cell Dev Biol . 2022 Sep; 10:967909. PMID: 36105360
Cells require major physical changes to induce a proper repartition of the DNA. Nuclear envelope breakdown, DNA condensation and spindle formation are promoted at mitotic entry by massive protein phosphorylation...
9.
Lacroix B, Dumont J
Cells . 2022 Jan; 11(2). PMID: 35053364
During cell division, the mitotic spindle, a macromolecular structure primarily comprised of microtubules, drives chromosome alignment and partitioning between daughter cells. Mitotic spindles can sense cellular dimensions in order to...
10.
Palenzuela H, Lacroix B, Salle J, Minami K, Shima T, Jegou A, et al.
Curr Biol . 2020 Sep; 30(22):4534-4540.e7. PMID: 32946749
The forces generated by microtubules (MTs) and their associated motors orchestrate essential cellular processes ranging from vesicular trafficking to centrosome positioning [1, 2]. To date, most studies have focused on...