Benjamin G Hoffstrom
Overview
Explore the profile of Benjamin G Hoffstrom including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
1170
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0
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Recent Articles
1.
Shabaneh T, Stevens A, Stull S, Shimp K, Seaton B, Gad E, et al.
J Immunother Cancer
. 2024 Feb;
12(2).
PMID: 38325903
Background: The paucity of tumor-specific targets for chimeric antigen receptor (CAR) T-cell therapy of solid tumors necessitates careful preclinical evaluation of the therapeutic window for candidate antigens. Human epidermal growth...
2.
Horr B, Kurtz R, Pandey A, Hoffstrom B, Schock E, Labonne C, et al.
Development
. 2023 Feb;
150(4).
PMID: 36789951
Monoclonal antibodies are powerful and versatile tools that enable the study of proteins in diverse contexts. They are often utilized to assist with identification of subcellular localization and characterization of...
3.
Sauer M, Tortorici M, Park Y, Walls A, Homad L, Acton O, et al.
Nat Struct Mol Biol
. 2021 May;
28(6):478-486.
PMID: 33981021
Three highly pathogenic β-coronaviruses have crossed the animal-to-human species barrier in the past two decades: SARS-CoV, MERS-CoV and SARS-CoV-2. To evaluate the possibility of identifying antibodies with broad neutralizing activity,...
4.
Godwin C, Laszlo G, Fiorenza S, Garling E, Phi T, Bates O, et al.
Leukemia
. 2021 Feb;
35(9):2496-2507.
PMID: 33589747
There is increasing interest in targeting CD33 in malignant and non-malignant disorders. In acute myeloid leukemia, longer survival with the CD33 antibody-drug conjugate gemtuzumab ozogamicin (GO) validates this strategy. Still,...
5.
Sauer M, Tortorici M, Park Y, Walls A, Homad L, Acton O, et al.
bioRxiv
. 2021 Jan;
PMID: 33398277
Three highly pathogenic β-coronaviruses crossed the animal-to-human species barrier in the past two decades: SARS-CoV, MERS-CoV and SARS-CoV-2. SARS-CoV-2 has infected more than 64 million people worldwide, claimed over 1.4...
6.
Pattwell S, Arora S, Cimino P, Ozawa T, Szulzewsky F, Hoellerbauer P, et al.
Nat Commun
. 2020 Jun;
11(1):2977.
PMID: 32532995
Independent scientific achievements have led to the discovery of aberrant splicing patterns in oncogenesis, while more recent advances have uncovered novel gene fusions involving neurotrophic tyrosine receptor kinases (NTRKs) in...
7.
Feng H, Schorpp K, Jin J, Yozwiak C, Hoffstrom B, Decker A, et al.
Cell Rep
. 2020 Mar;
30(10):3411-3423.e7.
PMID: 32160546
Ferroptosis is a type of regulated cell death driven by the iron-dependent accumulation of oxidized polyunsaturated fatty acid-containing phospholipids. There is no reliable way to selectively stain ferroptotic cells in...
8.
Balakrishnan A, Goodpaster T, Randolph-Habecker J, Hoffstrom B, Jalikis F, Koch L, et al.
Clin Cancer Res
. 2016 Nov;
23(12):3061-3071.
PMID: 27852699
This study examines cell surface ROR1 expression in human tumors and normal tissues. ROR1 is considered a promising target for cancer therapy due to putative tumor-specific expression, and multiple groups...
9.
Johansen L, DeWald L, Shoemaker C, Hoffstrom B, Lear-Rooney C, Stossel A, et al.
Sci Transl Med
. 2015 Jun;
7(290):290ra89.
PMID: 26041706
Currently, no approved therapeutics exist to treat or prevent infections induced by Ebola viruses, and recent events have demonstrated an urgent need for rapid discovery of new treatments. Repurposing approved...
10.
Johansen L, Brannan J, Delos S, Shoemaker C, Stossel A, Lear C, et al.
Sci Transl Med
. 2013 Jun;
5(190):190ra79.
PMID: 23785035
Ebola viruses remain a substantial threat to both civilian and military populations as bioweapons, during sporadic outbreaks, and from the possibility of accidental importation from endemic regions by infected individuals....