Benjamin Feldman
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Explore the profile of Benjamin Feldman including associated specialties, affiliations and a list of published articles.
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24
Citations
757
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Recent Articles
11.
Hong S, Jang M, Brown J, McBride A, Feldman B
Development
. 2011 Jan;
138(4):787-95.
PMID: 21266414
Vertebrate mesoderm and endoderm formation requires signaling by Nodal-related ligands from the TGFβ superfamily. The factors that initiate Nodal-related gene transcription are unknown in most species and the relative contributions...
12.
Pei W, Kratz L, Bernardini I, Sood R, Yokogawa T, Dorward H, et al.
Development
. 2010 Jul;
137(15):2587-96.
PMID: 20627962
Costeff Syndrome, which is caused by mutations in the OPTIC ATROPHY 3 (OPA3) gene, is an early-onset syndrome characterized by urinary excretion of 3-methylglutaconic acid (MGC), optic atrophy and movement...
13.
Hong S, Levin C, Brown J, Wan H, Sherman B, Huang D, et al.
BMC Dev Biol
. 2010 Apr;
10:42.
PMID: 20423468
Background: Many species form extraembryonic tissues during embryogenesis, such as the placenta of humans and other viviparous mammals. Extraembryonic tissues have various roles in protecting, nourishing and patterning embryos. Prior...
14.
Huizing M, Dorward H, Ly L, Klootwijk E, Kleta R, Skovby F, et al.
Mol Genet Metab
. 2010 Mar;
100(2):149-54.
PMID: 20350831
3-Methylglutaconic aciduria type III (3-MGCA type III), caused by recessive mutations in the 2-exon gene OPA3, is characterized by early-onset bilateral optic atrophy, later-onset extrapyramidal dysfunction, and increased urinary excretion...
15.
Roessler E, Pei W, Ouspenskaia M, Karkera J, Velez J, Banerjee-Basu S, et al.
Mol Genet Metab
. 2009 Jun;
98(1-2):225-34.
PMID: 19553149
The cyclopic and laterality phenotypes in model organisms linked to disturbances in the generation or propagation of Nodal-like signals are potential examples of similar impairments resulting in birth defects in...
16.
Pei W, Feldman B
Dev Biol
. 2008 Dec;
326(1):201-11.
PMID: 19046963
Loss of the zebrafish Nodal-related protein Squint causes a spectrum of phenotypes including cyclopia and midline bifurcations (MB). Here we examine MBs and their relation to cyclopia in maternal-zygotic squint...
17.
Domene S, Roessler E, El-Jaick K, Snir M, Brown J, Velez J, et al.
Hum Mol Genet
. 2008 Sep;
17(24):3919-28.
PMID: 18791198
Holoprosencephaly (HPE) is the most common developmental anomaly of the human forebrain; however, the genetics of this heterogeneous and etiologically complex malformation is incompletely understood. Heterozygous mutations in SIX3, a...
18.
Brown J, Snir M, Noushmehr H, Kirby M, Hong S, Elkahloun A, et al.
Proc Natl Acad Sci U S A
. 2008 Aug;
105(34):12337-42.
PMID: 18719100
A major goal for developmental biologists is to define the behaviors and molecular contents of differentiating cells. We have devised a strategy for isolating cells from diverse embryonic regions and...
19.
Roessler E, Ouspenskaia M, Karkera J, Velez J, Kantipong A, Lacbawan F, et al.
Am J Hum Genet
. 2008 Jun;
83(1):18-29.
PMID: 18538293
Abnormalities of embryonic patterning are hypothesized to underlie many common congenital malformations in humans including congenital heart defects (CHDs), left-right disturbances (L-R) or laterality, and holoprosencephaly (HPE). Studies in model...
20.
Schroter C, Herrgen L, Cardona A, Brouhard G, Feldman B, Oates A
Dev Dyn
. 2008 Feb;
237(3):545-53.
PMID: 18265021
Vertebrate somitogenesis is a rhythmically repeated morphogenetic process. The dependence of somitogenesis dynamics on axial position and temperature has not been investigated systematically in any species. Here we use multiple...