Benjamin Chain
Overview
Explore the profile of Benjamin Chain including associated specialties, affiliations and a list of published articles.
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35
Citations
1664
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Recent Articles
1.
Nagano Y, Chain B
Front Immunol
. 2023 Nov;
14:1276106.
PMID: 37954585
T cell receptors (TR) underpin the diversity and specificity of T cell activity. As such, TR repertoire data is valuable both as an adaptive immune biomarker, and as a way...
2.
Otter A, Abbass H, Abiodun A, Alfarih M, Alldis Z, Altmann D, et al.
Science
. 2022 Jun;
377(6603):eabq1841.
PMID: 35699621
The Omicron, or Pango lineage B.1.1.529, variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) carries multiple spike mutations with high transmissibility and partial neutralizing antibody (nAb) escape. Vaccinated individuals...
3.
Howell R, Clarke M, Reuschl A, Chen T, Abbott-Imboden S, Singer M, et al.
NPJ Digit Med
. 2022 Feb;
5(1):18.
PMID: 35165389
The COVID-19 pandemic has pushed healthcare systems globally to a breaking point. The urgent need for effective and affordable COVID-19 treatments calls for repurposing combinations of approved drugs. The challenge...
4.
Govada L, Saridakis E, Kassen S, Bin-Ramzi A, Morgan R, Chain B, et al.
IUCrJ
. 2021 Jul;
8(Pt 4):678-683.
PMID: 34258015
C-C chemokine receptor 5 (CCR5) is a major co-receptor molecule used by HIV-1 to enter cells. This led to the hypothesis that stimulating an antibody response would block HIV with...
5.
Reynolds C, Pade C, Gibbons J, Butler D, Otter A, Menacho K, et al.
Science
. 2021 May;
PMID: 33931567
SARS-CoV-2 vaccine rollout has coincided with the spread of variants of concern. We investigated if single dose vaccination, with or without prior infection, confers cross protective immunity to variants. We...
6.
Manisty C, Treibel T, Jensen M, Semper A, Joy G, Gupta R, et al.
EBioMedicine
. 2021 Mar;
65:103259.
PMID: 33662833
Background: SARS-CoV-2 serology is used to identify prior infection at individual and at population level. Extended longitudinal studies with multi-timepoint sampling to evaluate dynamic changes in antibody levels are required...
7.
Reynolds C, Swadling L, Gibbons J, Pade C, Jensen M, Diniz M, et al.
Sci Immunol
. 2020 Dec;
5(54).
PMID: 33361161
Understanding the nature of immunity following mild/asymptomatic infection with SARS-CoV-2 is crucial to controlling the pandemic. We analyzed T cell and neutralizing antibody responses in 136 healthcare workers (HCW) 16-18...
8.
Marcinkiewicz J, Mazurek H, Majka G, Chain B
Pol Arch Intern Med
. 2020 Oct;
130(10):919-920.
PMID: 33016684
No abstract available.
9.
Sampson D, Yager T, Fox B, Shallcross L, McHugh L, Seldon T, et al.
BMC Med
. 2020 Sep;
18(1):293.
PMID: 32919476
An amendment to this paper has been published and can be accessed via the original article.
10.
Sampson D, Yager T, Fox B, Shallcross L, McHugh L, Seldon T, et al.
BMC Med
. 2020 Jul;
18(1):185.
PMID: 32690014
Background: There is an urgent need to develop biomarkers that stratify risk of bacterial infection in order to support antimicrobial stewardship in emergency hospital admissions. Methods: We used computational machine...