Benjamin A Blount
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Explore the profile of Benjamin A Blount including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
198
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Recent Articles
1.
Blount B, Lu X, Driessen M, Jovicevic D, Sanchez M, Ciurkot K, et al.
Cell Genom
. 2023 Nov;
3(11):100418.
PMID: 38020971
We describe construction of the synthetic yeast chromosome XI () and reveal the effects of redesign at non-coding DNA elements. The 660-kb synthetic yeast genome project (Sc2.0) chromosome was assembled...
2.
Schindler D, Walker R, Jiang S, Brooks A, Wang Y, Muller C, et al.
Cell
. 2023 Nov;
186(24):5237-5253.e22.
PMID: 37944512
Here, we report the design, construction, and characterization of a tRNA neochromosome, a designer chromosome that functions as an additional, de novo counterpart to the native complement of Saccharomyces cerevisiae....
3.
Xu X, Meier F, Blount B, Pretorius I, Ellis T, Paulsen I, et al.
Nat Commun
. 2023 Apr;
14(1):1984.
PMID: 37031253
Naturally evolved organisms typically have large genomes that enable their survival and growth under various conditions. However, the complexity of genomes often precludes our complete understanding of them, and limits...
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5.
Blount B, Ellis T
Synth Biol (Oxf)
. 2020 Sep;
3(1):ysy020.
PMID: 32995526
The Synthetic Genome Summer Course was convened with the aim of teaching a wide range of researchers the theory and practical skills behind recent advances in synthetic biology and synthetic...
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7.
Awan A, Blount B, Bell D, Shaw W, Ho J, McKiernan R, et al.
Nat Commun
. 2017 May;
8:15202.
PMID: 28469278
Fungi are a valuable source of enzymatic diversity and therapeutic natural products including antibiotics. Here we engineer the baker's yeast Saccharomyces cerevisiae to produce and secrete the antibiotic penicillin, a...
8.
Ceroni F, Blount B, Ellis T
Cell Syst
. 2016 Aug;
3(2):116-117.
PMID: 27559922
Engineered E. coli can be made to autonomously switch from growth to production by a modular two-gate system that reduces the burden of biosynthesis.
9.
Blount B, Driessen M, Ellis T
Sci Rep
. 2016 Jun;
6:26863.
PMID: 27240644
Existing yeast genomic DNA extraction methods are not ideally suited to extensive screening of colonies by PCR, due to being too lengthy, too laborious or yielding poor quality DNA and...
10.
Jovicevic D, Blount B, Ellis T
Bioessays
. 2014 Jul;
36(9):855-60.
PMID: 25048260
A team of US researchers recently reported the design, assembly and in vivo functionality of a synthetic chromosome III (SynIII) for the yeast Saccharomyces cerevisiae. The synthetic chromosome was assembled...