Benedikt Obermayer
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Explore the profile of Benedikt Obermayer including associated specialties, affiliations and a list of published articles.
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57
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1806
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Recent Articles
11.
Markus D, Pelletier A, Boube M, Port F, Boutros M, Payre F, et al.
PLoS Genet
. 2023 Oct;
19(10):e1011004.
PMID: 37903161
The last decade witnesses the emergence of the abundant family of smORF peptides, encoded by small ORF (<100 codons), whose biological functions remain largely unexplored. Bioinformatic analyses here identify hundreds...
12.
Kuhnisch J, Theisen S, Dartsch J, Fritsche-Guenther R, Kirchner M, Obermayer B, et al.
Cardiovasc Res
. 2023 Oct;
119(18):2902-2916.
PMID: 37842925
Aims: Mutation of the PRDM16 gene causes human dilated and non-compaction cardiomyopathy. The PRDM16 protein is a transcriptional regulator that affects cardiac development via Tbx5 and Hand1, thus regulating myocardial...
13.
Lechner L, Opitz R, Silver M, Krabusch P, Prentice A, Field M, et al.
Sci Transl Med
. 2023 Jul;
15(705):eadg1659.
PMID: 37467315
Increasing evidence points toward epigenetic variants as a risk factor for developing obesity. We analyzed DNA methylation of the (pro-opiomelanocortin) gene, which is pivotal for satiety regulation. We identified sex-specific...
14.
Gressier E, Schulte-Schrepping J, Petrov L, Brumhard S, Stubbemann P, Hiller A, et al.
Nat Immunol
. 2023 May;
24(6):979-990.
PMID: 37188942
Antiviral CD8 T cell immunity depends on the integration of various contextual cues, but how antigen-presenting cells (APCs) consolidate these signals for decoding by T cells remains unclear. Here, we...
15.
Obermayer B, Keilholz L, Conrad T, Frentsch M, Blau I, Vuong L, et al.
Front Immunol
. 2023 Mar;
14:1114368.
PMID: 36860867
The critical balance between intended and adverse effects in allogeneic hematopoietic stem cell transplantation (alloHSCT) depends on the fate of individual donor T-cells. To this end, we tracked αβT-cell clonotypes...
16.
Mothes R, Pascual-Reguant A, Koehler R, Liebeskind J, Liebheit A, Bauherr S, et al.
Nat Commun
. 2023 Feb;
14(1):791.
PMID: 36774347
Prolonged lung pathology has been associated with COVID-19, yet the cellular and molecular mechanisms behind this chronic inflammatory disease are poorly understood. In this study, we combine advanced imaging and...
17.
Baumgardt M, Hulsemann M, Lowa A, Fatykhova D, Hoffmann K, Kessler M, et al.
PLoS One
. 2022 Dec;
17(12):e0276115.
PMID: 36538516
Human-based organ models can provide strong predictive value to investigate the tropism, virulence, and replication kinetics of viral pathogens. Currently, such models have received widespread attention in the study of...
18.
Kedziora S, Obermayer B, Sugulle M, Herse F, Kraker K, Haase N, et al.
Int J Mol Sci
. 2022 Dec;
23(23).
PMID: 36499721
The placenta is a temporary organ with a unique structure and function to ensure healthy fetal development. Placental dysfunction is involved in pre-eclampsia (PE), fetal growth restriction, preterm birth, and...
19.
Bertrams W, Honzke K, Obermayer B, Tonnies M, Bauer T, Schneider P, et al.
Sci Rep
. 2022 Nov;
12(1):20608.
PMID: 36446841
Influenza A virus (IAV) causes pandemics and annual epidemics of severe respiratory infections. A better understanding of the molecular regulation in tissue and cells upon IAV infection is needed to...
20.
Dorr D, Obermayer B, Weiner J, Zimmermann K, Anania C, Wagner L, et al.
Sci Immunol
. 2022 Sep;
7(75):eabj0140.
PMID: 36112694
Pulmonary alveolar proteinosis (PAP) is a syndrome characterized by accumulation of surfactant lipoproteins within the lung alveoli. Alveolar macrophages (AMs) are crucial for surfactant clearance, and their differentiation depends on...