Benedicte Buttard
Overview
Explore the profile of Benedicte Buttard including associated specialties, affiliations and a list of published articles.
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13
Citations
4083
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Recent Articles
1.
El Sissy C, Kirilovsky A, Lagorce Pages C, Marliot F, Custers P, Dizdarevic E, et al.
J Clin Oncol
. 2023 Oct;
42(1):70-80.
PMID: 37788410
Purpose: No biomarker capable of improving selection and monitoring of patients with rectal cancer managed by watch-and-wait (W&W) strategy is currently available. Prognostic performance of the Immunoscore biopsy (IS) was...
2.
Willis J, Anders R, Torigoe T, Hirohashi Y, Bifulco C, Zlobec I, et al.
Cancers (Basel)
. 2023 Aug;
15(16).
PMID: 37627073
Background: The Immunoscore (IS) is a quantitative digital pathology assay that evaluates the immune response in cancer patients. This study reports on the reproducibility of pathologists' visual assessment of CD3+-...
3.
Mlecnik B, Lugli A, Bindea G, Marliot F, Bifulco C, Lee J, et al.
Cancers (Basel)
. 2023 Jan;
15(2).
PMID: 36672367
Background: The prognostic value of Immunoscore was evaluated in Stage II/III colon cancer (CC) patients, but it remains unclear in Stage I/II, and in early-stage subgroups at risk. An international...
4.
Mlecnik B, Torigoe T, Bindea G, Popivanova B, Xu M, Fujita T, et al.
Cancers (Basel)
. 2022 Sep;
14(18).
PMID: 36139506
BACKGROUND: In this study, we evaluated the prognostic value of Immunoscore in patients with stage I−III colon cancer (CC) in the Asian population. These patients were originally included in an...
5.
Ramos R, Missolo-Koussou Y, Gerber-Ferder Y, Bromley C, Bugatti M, Gonzalo Nunez N, et al.
Cell
. 2022 Mar;
185(7):1189-1207.e25.
PMID: 35325594
Macrophage infiltration is a hallmark of solid cancers, and overall macrophage infiltration correlates with lower patient survival and resistance to therapy. Tumor-associated macrophages, however, are phenotypically and functionally heterogeneous. Specific...
6.
Mlecnik B, Bifulco C, Bindea G, Marliot F, Lugli A, Lee J, et al.
J Clin Oncol
. 2020 Sep;
38(31):3638-3651.
PMID: 32897827
Purpose: The purpose of this study was to evaluate the prognostic value of Immunoscore in patients with stage III colon cancer (CC) and to analyze its association with the effect...
7.
Mascaux C, Angelova M, Vasaturo A, Beane J, Hijazi K, Anthoine G, et al.
Nature
. 2019 Jun;
571(7766):570-575.
PMID: 31243362
Early detection and treatment are critical for improving the outcome of patients with cancer. Understanding the largely uncharted biology of carcinogenesis requires deciphering molecular processes in premalignant lesions, and revealing...
8.
Angelova M, Mlecnik B, Vasaturo A, Bindea G, Fredriksen T, Lafontaine L, et al.
Cell
. 2018 Oct;
175(3):751-765.e16.
PMID: 30318143
We examined how the immune microenvironment molds tumor evolution at different metastatic organs in a longitudinal dataset of colorectal cancer. Through multiplexed analyses, we showed that clonal evolution patterns during...
9.
Pages F, Mlecnik B, Marliot F, Bindea G, Ou F, Bifulco C, et al.
Lancet
. 2018 May;
391(10135):2128-2139.
PMID: 29754777
Background: The estimation of risk of recurrence for patients with colon carcinoma must be improved. A robust immune score quantification is needed to introduce immune parameters into cancer classification. The...
10.
Giraldo N, Becht E, Vano Y, Petitprez F, Lacroix L, Validire P, et al.
Clin Cancer Res
. 2017 Feb;
23(15):4416-4428.
PMID: 28213366
The efficacy of PD-1 checkpoint blockade as adjuvant therapy in localized clear cell renal cell carcinoma (ccRCC) is currently unknown. The identification of tumor microenvironment (TME) prognostic biomarkers in this...