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Ben Nicholas

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Articles 22
Citations 1068
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Recent Articles
1.
Nicholas B, Bailey A, McCann K, Walker R, Johnson P, Elliott T, et al.
PLoS One . 2025 Mar; 20(3):e0318572. PMID: 40073002
Oesophageal adenocarcinoma (OAC) is the 7th most common cancer in the United Kingdom (UK) and remains a significant health challenge. This study presents a proteomic analysis of seven OAC donors...
2.
Nicholas B, Bailey A, McCann K, Johnson P, Elliott T, Ottensmeier C, et al.
J Proteome Res . 2025 Jan; 24(2):729-741. PMID: 39772544
Non-small cell lung cancer (NSCLC) is frequently diagnosed late and has poor survival. The two predominant subtypes of NSCLC, adenocarcinoma (LUAD) and squamous cell carcinoma (LUSC), are currently differentially diagnosed...
3.
Nicholas B, Skipp P
Essays Biochem . 2023 Jul; 67(6):957-965. PMID: 37503576
Immunopeptidomics is the survey of all peptides displayed on a cell or tissue when bound to human leukocyte antigen (HLA) molecules using tandem mass spectrometry. When attempting to determine the...
4.
Nicholas B, Lee H, Guo J, Cicmil M, Blume C, De Waal Malefyt R, et al.
Front Immunol . 2022 Dec; 13:973673. PMID: 36479132
Asthmatics are more susceptible to viral infections than healthy individuals and are known to have impaired innate anti-viral defences. Influenza A virus causes significant morbidity and mortality in this population....
5.
Nicholas B, Bailey A, McCann K, Wood O, Walker R, Parker R, et al.
Immunology . 2022 Sep; 168(3):420-431. PMID: 36111495
Oesophageal adenocarcinoma (OAC) has a relatively poor long-term survival and limited treatment options. Promising targets for immunotherapy are short peptide neoantigens containing tumour mutations, presented to cytotoxic T-cells by human...
6.
Nicholas B, Guo J, Lee H, Bailey A, De Waal Malefyt R, Cicmil M, et al.
Clin Exp Allergy . 2022 Jul; 52(11):1334-1337. PMID: 35892202
No abstract available.
7.
Nicholas B, Bailey A, Staples K, Wilkinson T, Elliott T, Skipp P
PLoS Pathog . 2022 Jan; 18(1):e1009894. PMID: 35051231
CD8+ and CD4+ T cells provide cell-mediated cross-protection against multiple influenza strains by recognising epitopes bound as peptides to human leukocyte antigen (HLA) class I and -II molecules respectively. Two...
8.
Bailey A, Nicholas B, Darley R, Parkinson E, Teo Y, Aleksic M, et al.
Toxicol Sci . 2020 Dec; 180(1):136-147. PMID: 33372950
Skin sensitization following the covalent modification of proteins by low molecular weight chemicals (haptenation) is mediated by cytotoxic T lymphocyte (CTL) recognition of human leukocyte antigen (HLA) molecules presented on...
9.
Schofield J, Burg D, Nicholas B, Strazzeri F, Brandsma J, Staykova D, et al.
J Allergy Clin Immunol . 2019 Apr; 144(1):70-82. PMID: 30928653
Background: Stratification by eosinophil and neutrophil counts increases our understanding of asthma and helps target therapy, but there is room for improvement in our accuracy in prediction of treatment responses...
10.
Burg D, Schofield J, Brandsma J, Staykova D, Folisi C, Bansal A, et al.
J Proteome Res . 2018 May; 17(6):2072-2091. PMID: 29737851
Analysis of induced sputum supernatant is a minimally invasive approach to study the epithelial lining fluid and, thereby, provide insight into normal lung biology and the pathobiology of lung diseases....