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Ben Meulders

Explore the profile of Ben Meulders including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 7
Citations 7
Followers 0
Related Specialties
Science
General Medicine
Biochemistry
Co-Authors
Waleed F A Marei
Jo L M R Leroy
Inne Xhonneux
Peter E J Bols
Lien Loier
Silke Andries
Isabel Pintelon
Jens Slootmans
Anouk Smits
Published In
Front Physiol
Int J Mol Sci
Reproduction
PLoS One
Sci Rep
Affiliations
Soon will be listed here.
Recent Articles
1.
Lipotoxicity and Oocyte Quality in Mammals: Pathogenesis, Consequences, and Reversibility
Meulders B, Marei W, Loier L, Leroy J
Annu Rev Anim Biosci . 2024 Nov; 13(1):233-254. PMID: 39565833
Metabolic stress conditions are often characterized by upregulated lipolysis and subsequently increased serum free fatty acid (FFA) concentrations, leading to the uptake of FFAs by non-adipose tissues and impairment of...
2.
The impact of offspring and maternal obesogenic diets on adult offspring oocyte mitochondrial morphology in primordial and preantral follicles
Xhonneux I, Marei W, Meulders B, Slootmans J, Pintelon I, Leroy J
PLoS One . 2024 Jun; 19(6):e0305912. PMID: 38935642
Diet-induced obesity reduces oocyte quality mainly by impacting oocyte mitochondrial functions. Moreover, maternal obesity is associated with mitochondrial dysfunction in oocytes of their adult offspring. However, these effects were reported...
3.
The interplay of maternal and offspring obesogenic diets: the impact on offspring metabolism and muscle mitochondria in an outbred mouse model
Xhonneux I, Marei W, Meulders B, Andries S, Leroy J
Front Physiol . 2024 Apr; 15:1354327. PMID: 38585221
Consumption of obesogenic (OB) diets increases the prevalence of maternal obesity worldwide, causing major psychological and social burdens in women. Obesity not only impacts the mother's health and fertility but...
4.
Preconception Diet Interventions in Obese Outbred Mice and the Impact on Female Offspring Metabolic Health and Oocyte Quality
Meulders B, Marei W, Xhonneux I, Loier L, Smits A, Leroy J
Int J Mol Sci . 2024 Feb; 25(4). PMID: 38396912
Obese individuals often suffer from metabolic health disorders and reduced oocyte quality. Preconception diet interventions in obese outbred mice restore metabolic health and oocyte quality and mitochondrial ultrastructure. Also, studies...
5.
Effect of lipotoxicity on mitochondrial function and epigenetic programming during bovine in vitro embryo production
Meulders B, Marei W, Xhonneux I, Bols P, Leroy J
Sci Rep . 2023 Dec; 13(1):21664. PMID: 38066095
Maternal metabolic disorders may cause lipotoxic effects on the developing oocyte. Understanding the timing at which this might disrupt embryo epigenetic programming and how this is linked with mitochondrial dysfunction...
6.
In vitro reduction of bovine oocyte ATP production with oligomycin affects embryo epigenome
Meulders B, Leroy J, Xhonneux I, Bols P, Marei W
Reproduction . 2023 Dec; 167(2). PMID: 38038651
In Brief: Epigenetic programming is a crucial process during early embryo development that can have a significant impact on the results of assisted reproductive technology (ART) and offspring health. Here...
7.
The impact of a maternal and offspring obesogenic diet on daughter's oocyte mitochondrial ultrastructure and bioenergetic responses. Insights from an outbred mouse model
Xhonneux I, Marei W, Meulders B, Andries S, Leroy J
Front Physiol . 2023 Nov; 14:1288472. PMID: 37965107
Obesity affects oocyte mitochondrial functions and reduces oocyte quality and fertility. Obesity may also increase the risk of metabolic disorders in the offspring. Children are likely to follow their parents...