Behnom Farboud
Overview
Explore the profile of Behnom Farboud including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
362
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0
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Recent Articles
1.
Farboud B, Novak C, Nicoll M, Quiogue A, Meyer B
Elife
. 2020 Dec;
9.
PMID: 33372658
We demonstrate how RNA binding protein FOX-1 functions as a dose-dependent X-signal element to communicate X-chromosome number and thereby determine nematode sex. FOX-1, an RNA recognition motif protein, triggers hermaphrodite...
2.
Farboud B, Severson A, Meyer B
Genetics
. 2018 Dec;
211(2):431-457.
PMID: 30504364
The targetable DNA endonuclease CRISPR-Cas9 has transformed analysis of biological processes by enabling robust genome editing in model and nonmodel organisms. Although rules directing Cas9 to its target DNA via...
3.
Farboud B, Jarvis E, Roth T, Shin J, Corn J, Marson A, et al.
J Vis Exp
. 2018 Jun;
(135).
PMID: 29889198
Site-specific eukaryotic genome editing with CRISPR (clustered regularly interspaced short palindromic repeats)-Cas (CRISPR-associated) systems has quickly become a commonplace amongst researchers pursuing a wide variety of biological questions. Users most...
4.
Farboud B
Wiley Interdiscip Rev Dev Biol
. 2017 Aug;
6(6).
PMID: 28810059
Utilization of programmable nucleases to generate DNA lesions at precise endogenous sequences has transformed the ability to edit genomes from microbes to plants and animals. This is especially true in...
5.
Farboud B, Meyer B
Genetics
. 2015 Feb;
199(4):959-71.
PMID: 25695951
Success with genome editing by the RNA-programmed nuclease Cas9 has been limited by the inability to predict effective guide RNAs and DNA target sites. Not all guide RNAs have been...
6.
Farboud B, Nix P, Jow M, Gladden J, Meyer B
Genes Dev
. 2013 May;
27(10):1159-78.
PMID: 23666922
Sex is determined in Caenorhabditis elegans by the ratio of X chromosomes to the sets of autosomes, the X:A signal. A set of genes called X signal elements (XSEs) communicates...
7.
Goodson M, Farboud B, Privalsky M
Methods Mol Biol
. 2009 Jan;
505:157-69.
PMID: 19117144
Various assays have been employed to study the nuclear receptor/cofactor interactions. Coimmunoprecipitation protocols, both yeast and mammalian two-hybrid systems, and electrophoretic mobility shift/supershift assays are all commonly used. One of...
8.
Gladden J, Farboud B, Meyer B
Genetics
. 2007 Oct;
177(3):1639-54.
PMID: 17947428
In Caenorhabditis elegans, sex is determined by the opposing actions of X-signal elements (XSEs) and autosomal signal elements (ASEs), which communicate the ratio of X chromosomes to sets of autosomes...
9.
Goodson M, Farboud B, Privalsky M
Nucl Recept Signal
. 2007 Apr;
5:e002.
PMID: 17464356
The Glutathione-S-Transferase (GST) "pulldown" assay has been used extensively to assay protein interactions in vitro. This methodology has been especially useful for investigating the interactions of nuclear hormone receptors with...
10.
Wan W, Farboud B, Privalsky M
Mol Endocrinol
. 2005 Apr;
19(6):1529-42.
PMID: 15802373
Resistance to thyroid hormone (RTH) syndrome is an inherited inability to respond appropriately to T3 hormone. In generalized RTH, the T3 response of both the pituitary and periphery is disrupted....