Beatriz Lopez-Corcuera
Overview
Explore the profile of Beatriz Lopez-Corcuera including associated specialties, affiliations and a list of published articles.
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Articles
27
Citations
319
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Recent Articles
1.
de la Rocha-Munoz A, Nunez E, Vishwanath A, Gomez-Lopez S, Dhanasobhon D, Rebola N, et al.
Commun Biol
. 2021 Oct;
4(1):1197.
PMID: 34663888
The identity of a glycinergic synapse is maintained presynaptically by the activity of a surface glycine transporter, GlyT2, which recaptures glycine back to presynaptic terminals to preserve vesicular glycine content....
2.
Benito-Munoz C, Perona A, Felipe R, Perez-Siles G, Nunez E, Aragon C, et al.
ACS Chem Neurosci
. 2021 May;
12(11):1860-1872.
PMID: 34003005
The neuronal glycine transporter GlyT2 modulates inhibitory glycinergic neurotransmission by controlling the extracellular concentration of synaptic glycine and the supply of neurotransmitter to the presynaptic terminal. Spinal cord glycinergic neurons...
3.
Danbolt N, Lopez-Corcuera B, Zhou Y
Neurochem Res
. 2021 Apr;
47(1):85-110.
PMID: 33905037
In contrast to water soluble enzymes which can be purified and studied while in solution, studies of solute carrier (transporter) proteins require both that the protein of interest is situated...
4.
de la Rocha-Munoz A, Melgarejo E, Aragon C, Lopez-Corcuera B
Neuropharmacology
. 2021 Apr;
189:108543.
PMID: 33794243
Hyperekplexia is a rare sensorimotor syndrome characterized by pathological startle reflex in response to unexpected trivial stimuli for which there is no specific treatment. Neonates suffer from hypertonia and are...
5.
Jimenez E, Fornes A, Felipe R, Nunez E, Aragon C, Lopez-Corcuera B
Neurochem Res
. 2021 Mar;
47(1):190-203.
PMID: 33765249
The neuronal glycine transporter GlyT2 modulates inhibitory glycinergic neurotransmission and plays a key role in regulating nociceptive signal progression. The cholinergic system acting through muscarinic acetylcholine receptors (mAChRs) also mediates...
6.
Benito-Munoz C, Perona A, Abia D, Santos H, Nunez E, Aragon C, et al.
Front Mol Neurosci
. 2018 Oct;
11:347.
PMID: 30319354
Neurotransmitter removal from glycine-mediated synapses relies on two sodium-driven high-affinity plasma membrane GlyTs that control neurotransmitter availability. Mostly glial GlyT1 is the main regulator of glycine synaptic levels, whereas neuronal...
7.
Lopez-Corcuera B, Arribas-Gonzalez E, Aragon C
Neurochem Int
. 2018 Jun;
123:95-100.
PMID: 29859229
Hyperekplexia or startle disease is a dysfunction of inhibitory glycinergic neurotransmission characterized by an exaggerated startle in response to trivial tactile or acoustic stimuli. Although rare, this disorder can have...
8.
Lopez-Corcuera B, Benito-Munoz C, Aragon C
Adv Neurobiol
. 2017 Aug;
16:13-32.
PMID: 28828604
Glycine, besides exerting essential metabolic functions, is an important inhibitory neurotransmitter in caudal areas of the central nervous system and also a positive neuromodulator at excitatory glutamate-mediated synapses. Glial cells...
9.
Villarejo-Lopez L, Jimenez E, Bartolome-Martin D, Zafra F, Lapunzina P, Aragon C, et al.
Neuropharmacology
. 2017 Jul;
125:99-116.
PMID: 28734869
Glycinergic inhibitory neurons of the spinal dorsal horn exert critical control over the conduction of nociceptive signals to higher brain areas. The neuronal glycine transporter 2 (GlyT2) is involved in...
10.
Arribas-Gonzalez E, de Juan-Sanz J, Aragon C, Lopez-Corcuera B
J Biol Chem
. 2014 Dec;
290(4):2150-65.
PMID: 25480793
Hyperekplexia or startle disease is a rare clinical syndrome characterized by an exaggerated startle in response to trivial tactile or acoustic stimuli. This neurological disorder can have serious consequences in...