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Beata Wielgus-Kutrowska

Explore the profile of Beata Wielgus-Kutrowska including associated specialties, affiliations and a list of published articles. Areas
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Articles 43
Citations 219
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Recent Articles
1.
Stachelska-Wierzchowska A, Narczyk M, Wierzchowski J, Bzowska A, Wielgus-Kutrowska B
Int J Mol Sci . 2024 Oct; 25(19). PMID: 39408755
Fluorescent markers play important roles in spectroscopic and microscopic research techniques and are broadly used in basic and applied sciences. We have obtained markers with fluorescent properties, two etheno derivatives...
2.
Wielgus-Kutrowska B, Wierzchowski J, Stachelska-Wierzchowska A, Krasowska J, Lee B, Pham D, et al.
Luminescence . 2024 Aug; 39(8):e4865. PMID: 39160141
We studied spectral properties of 1,N-etheno-2-aminopurine after immobilization in poly (vinyl alcohol) films. The absorption spectrum of 1,N-ε2APu consists of two peaks centered at 300 and 370 nm, and the...
3.
Miskovic M, Wojtys M, Winiewska-Szajewska M, Wielgus-Kutrowska B, Matkovic M, Domazet Jurasin D, et al.
Int J Mol Sci . 2024 Jul; 25(14). PMID: 39062851
The requirement for fast and dependable protein purification methods is constant, either for functional studies of natural proteins or for the production of biotechnological protein products. The original procedure has...
4.
Dyzma A, Wielgus-Kutrowska B, Girstun A, Jelic Matosevic Z, Staron K, Bertosa B, et al.
Int J Mol Sci . 2023 Feb; 24(3). PMID: 36768477
Mammalian purine nucleoside phosphorylase (PNP) is biologically active as a homotrimer, in which each monomer catalyzes a reaction independently of the others. To answer the question of why the native...
5.
Bubic A, Narczyk M, Petek A, Wojtys M, Maksymiuk W, Wielgus-Kutrowska B, et al.
Int J Biol Macromol . 2022 Dec; 226:37-50. PMID: 36470440
Purine nucleotide synthesis is realised only through the salvage pathway in pathogenic bacterium Helicobacter pylori. Therefore, the enzymes of this pathway, among them also the adenylosuccinate synthetase (AdSS), present potential...
6.
Wielgus-Kutrowska B, Marcisz U, Antosiewicz J
J Phys Chem B . 2021 Sep; 125(38):10701-10709. PMID: 34546051
Using stopped-flow fluorometry, we determined rate constants for the formation of diffusional encounter complexes of tri--acetylglucosamine (NAG) with hen egg-white lysozyme () and its double mutant Asp48Asn/Lys116Gln (). We defined...
7.
Krasowska J, Pierzchala K, Bzowska A, Forro L, Sienkiewicz A, Wielgus-Kutrowska B
Int J Mol Sci . 2021 Aug; 22(16). PMID: 34445269
Under stress conditions, elevated levels of cellular reactive oxygen species (ROS) may impair crucial cellular structures. To counteract the resulting oxidative damage, living cells are equipped with several defense mechanisms,...
8.
Narczyk M, Mioduszewski L, Oksiejuk A, Winiewska-Szajewska M, Wielgus-Kutrowska B, Gojdz A, et al.
Sci Rep . 2021 May; 11(1):11144. PMID: 34045551
E. coli purine nucleoside phosphorylase is a homohexamer, which structure, in the apo form, can be described as a trimer of dimers. Earlier studies suggested that ligand binding and kinetic...
9.
Dawidziak-Pakula A, Krasowska J, Wielgus-Kutrowska B
Acta Biochim Pol . 2020 Mar; 67(1):85-91. PMID: 32188237
Enhanced green fluorescent protein (EGFP) is a fluorescent marker used in bio-imaging applications, including as an indicator of folding or aggregation of a fused partner. However, the limited maturation, low...
10.
Stachelska-Wierzchowska A, Wierzchowski J, Gorka M, Bzowska A, Stolarski R, Wielgus-Kutrowska B
Molecules . 2020 Feb; 25(3). PMID: 32033464
Etheno-derivatives of 2-aminopurine, 2-aminopurine riboside, and 7-deazaadenosine (tubercidine) were prepared and purified using standard methods. 2-Aminopurine reacted with aqueous chloroacetaldehyde to give two products, both exhibiting substrate activity towards bacterial...