Alicja Stachelska-Wierzchowska
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Explore the profile of Alicja Stachelska-Wierzchowska including associated specialties, affiliations and a list of published articles.
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14
Citations
48
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Recent Articles
1.
Stachelska-Wierzchowska A, Narczyk M, Wierzchowski J, Bzowska A, Wielgus-Kutrowska B
Int J Mol Sci
. 2024 Oct;
25(19).
PMID: 39408755
Fluorescent markers play important roles in spectroscopic and microscopic research techniques and are broadly used in basic and applied sciences. We have obtained markers with fluorescent properties, two etheno derivatives...
2.
Wielgus-Kutrowska B, Wierzchowski J, Stachelska-Wierzchowska A, Krasowska J, Lee B, Pham D, et al.
Luminescence
. 2024 Aug;
39(8):e4865.
PMID: 39160141
We studied spectral properties of 1,N-etheno-2-aminopurine after immobilization in poly (vinyl alcohol) films. The absorption spectrum of 1,N-ε2APu consists of two peaks centered at 300 and 370 nm, and the...
3.
Stachelska-Wierzchowska A, Wierzchowski J
Biomolecules
. 2024 Jun;
14(6).
PMID: 38927104
Chemo-enzymatic syntheses of strongly fluorescent nucleoside analogs, potentially applicable in analytical biochemistry and cell biology are reviewed. The syntheses and properties of fluorescent ribofuranosides of several purine, 8-azapurine, and etheno-purine...
4.
Kaminski J, Stachelska-Wierzchowska A, Michalczyk D, Klimkowicz-Pawlas A, Olkowska E, Wolska L, et al.
Molecules
. 2024 May;
29(10).
PMID: 38792197
The impact of fluorine on plants remains poorly understood. We examined duckweed growth in extracts of soil contaminated with fluorine leached from chicken manure. Additionally, fluorine levels were analyzed in...
5.
Stachelska-Wierzchowska A, Wierzchowski J, Gorka M, Bzowska A, Stolarski R, Wielgus-Kutrowska B
Molecules
. 2020 Feb;
25(3).
PMID: 32033464
Etheno-derivatives of 2-aminopurine, 2-aminopurine riboside, and 7-deazaadenosine (tubercidine) were prepared and purified using standard methods. 2-Aminopurine reacted with aqueous chloroacetaldehyde to give two products, both exhibiting substrate activity towards bacterial...
6.
Stachelska-Wierzchowska A, Wierzchowski J
Acta Biochim Pol
. 2019 Dec;
66(4):585-588.
PMID: 31804790
Fluorescent tri-cyclic purine analogs, derivatives of isoguanine and adenine, were examined as potential substrates of purine-nucleoside phosphorylase. It was found previously that etheno- derivatives of both compounds are ribosylated in...
7.
Stachelska-Wierzchowska A, Wierzchowski J, Gorka M, Bzowska A, Wielgus-Kutrowska B
Molecules
. 2019 Apr;
24(8).
PMID: 30995785
Etheno-derivatives of guanine, -methylguanine, and isoguanine were prepared and purified using standard methods. The title compounds were examined as potential substrates of purine-nucleoside phosphorylases from various sources in the reverse...
8.
Stachelska-Wierzchowska A, Wierzchowski J, Bzowska A, Wielgus-Kutrowska B
Nucleosides Nucleotides Nucleic Acids
. 2018 Jan;
37(2):89-101.
PMID: 29376769
The title compound is an excellent substrate for E. coli PNP, as well as for its D204N mutant. The main product of the synthetic reaction is N9-riboside, but some amount...
9.
Wierzchowski J, Stachelska-Wierzchowska A, Wielgus-Kutrowska B, Bzowska A
Curr Pharm Des
. 2017 Oct;
PMID: 29022509
Background: Purine-nucleoside phosphorylase (PNP) is known as a tool for the synthesis of various nucleosides and nucleoside analogues. Mechanism, properties, molecular diversity and inhibitors of PNP, particularly these of pharmacological...
10.
Stachelska-Wierzchowska A, Wierzchowski J, Bzowska A, Wielgus-Kutrowska B
Molecules
. 2016 Jan;
21(1):E44.
PMID: 26729076
Enzymatic ribosylation of fluorescent 8-azapurine derivatives, like 8-azaguanine and 2,6-diamino-8-azapurine, with purine-nucleoside phosphorylase (PNP) as a catalyst, leads to N9, N8, and N7-ribosides. The final proportion of the products may...