Batool Shannan
Overview
Explore the profile of Batool Shannan including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
16
Citations
548
Followers
0
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Recent Articles
11.
Zhang G, Frederick D, Wu L, Wei Z, Krepler C, Srinivasan S, et al.
J Clin Invest
. 2016 Apr;
126(5):1834-56.
PMID: 27043285
Targeting multiple components of the MAPK pathway can prolong the survival of patients with BRAFV600E melanoma. This approach is not curative, as some BRAF-mutated melanoma cells are intrinsically resistant to...
12.
Shannan B, Chen Q, Watters A, Perego M, Krepler C, Thombre R, et al.
Pigment Cell Melanoma Res
. 2016 Feb;
29(3):317-28.
PMID: 26850518
Targeted therapies for mutant BRAF metastatic melanoma are effective but not curative due to acquisition of resistance. PI3K signaling is a common mediator of therapy resistance in melanoma; thus, the...
13.
Krepler C, Xiao M, Sproesser K, Brafford P, Shannan B, Beqiri M, et al.
Clin Cancer Res
. 2015 Dec;
22(7):1592-602.
PMID: 26673799
Purpose: To test second-line personalized medicine combination therapies, based on genomic and proteomic data, in patient-derived xenograft (PDX) models. Experimental Design: We established 12 PDXs from BRAF inhibitor-progressed melanoma patients....
14.
Shannan B, Perego M, Somasundaram R, Herlyn M
Cancer Treat Res
. 2015 Nov;
167:1-15.
PMID: 26601857
Melanoma is among the most aggressive and therapy-resistant human cancers. While great strides in therapy have generated enthusiasm, many challenges remain. Heterogeneity is the most pressing issue for all types...
15.
Kastl A, Dieckmann S, Wahler K, Volker T, Kastl L, Merkel A, et al.
ChemMedChem
. 2013 Apr;
8(6):924-7.
PMID: 23568508
Shedding light on the matter: Rhenium(I) indolato complexes with highly potent visible-light-triggered antiproliferative activity (complex 1: EC50 light=0.1 μM vs EC50 dark=100 μM) in 2D- and 3D-organized cancer cells are...
16.
Obeid R, Shannan B, Herrmann W
Med Hypotheses
. 2011 Sep;
77(5):884-8.
PMID: 21880434
Advanced glycation end products (AGEs) contribute to aging. Cobalamin (Cbl) is required for cell growth and functions, and its deficiency causes serious complications. Diabetics and renal patients show high concentrations...