Bastian Zimmer
Overview
Explore the profile of Bastian Zimmer including associated specialties, affiliations and a list of published articles.
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23
Citations
1068
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Recent Articles
11.
Aschner M, Ceccatelli S, Daneshian M, Fritsche E, Hasiwa N, Hartung T, et al.
ALTEX
. 2016 Jul;
34(1):49-74.
PMID: 27452664
There is a paucity of information concerning the developmental neurotoxicity (DNT) hazard posed by industrial and environmental chemicals. New testing approaches will most likely be based on batteries of alternative...
12.
Zimmer B, Piao J, Ramnarine K, Tomishima M, Tabar V, Studer L
Stem Cell Reports
. 2016 Jun;
6(6):858-872.
PMID: 27304916
Human pluripotent stem cells (hPSCs) provide an unlimited cell source for regenerative medicine. Hormone-producing cells are particularly suitable for cell therapy, and hypopituitarism, a defect in pituitary gland function, represents...
13.
Fattahi F, Steinbeck J, Kriks S, Tchieu J, Zimmer B, Kishinevsky S, et al.
Nature
. 2016 Feb;
531(7592):105-9.
PMID: 26863197
The enteric nervous system (ENS) is the largest component of the autonomic nervous system, with neuron numbers surpassing those present in the spinal cord. The ENS has been called the...
14.
Dreser N, Zimmer B, Dietz C, Sugis E, Pallocca G, Nyffeler J, et al.
Neurotoxicology
. 2015 Aug;
50:56-70.
PMID: 26238599
Functional assays, such as the "migration inhibition of neural crest cells" (MINC) developmental toxicity test, can identify toxicants without requiring knowledge on their mode of action (MoA). Here, we were...
15.
Sisnaiske J, Hausherr V, Krug A, Zimmer B, Hengstler J, Leist M, et al.
Neurotoxicology
. 2014 Apr;
43:117-126.
PMID: 24726791
Stem cell-derived specialized cell types are of interest as an alternative cell system to identify and research neurotoxic effects and modes of action. Developmental toxicity may be studied during differentiation,...
16.
Dincer Z, Piao J, Niu L, Ganat Y, Kriks S, Zimmer B, et al.
Cell Rep
. 2013 Dec;
5(5):1387-402.
PMID: 24290755
Cranial placodes are embryonic structures essential for sensory and endocrine organ development. Human placode development has remained largely inaccessible despite the serious medical conditions caused by the dysfunction of placode-derived...
17.
Balmer N, Weng M, Zimmer B, Ivanova V, Chambers S, Nikolaeva E, et al.
Hum Mol Genet
. 2012 Jun;
21(18):4104-14.
PMID: 22723015
Exposure to the antiepileptic drug valproic acid (VPA) during gestation causes neurofunctional and anatomic deficits in later life. At present, there are little human data on how early neural development...
18.
Kadereit S, Zimmer B, van Thriel C, Hengstler J, Leist M
Front Biosci (Landmark Ed)
. 2012 Jun;
17(7):2442-60.
PMID: 22652791
Development of in vitro systems, such as those based on embryonic stem cell differentiation, depends on the selection of adequate test and training compounds. We recommend the use of two...
19.
Weng M, Zimmer B, Poltl D, Broeg M, Ivanova V, Gaspar J, et al.
PLoS One
. 2012 May;
7(5):e36708.
PMID: 22590590
Epigenetic changes, including histone modifications or chromatin remodeling are regulated by a large number of human genes. We developed a strategy to study the coordinate regulation of such genes, and...
20.
Zimmer B, Lee G, Balmer N, Meganathan K, Sachinidis A, Studer L, et al.
Environ Health Perspect
. 2012 May;
120(8):1116-22.
PMID: 22571897
Background: Information on the potential developmental toxicity (DT) of the majority of chemicals is scarce, and test capacities for further animal-based testing are limited. Therefore, new approaches with higher throughput...