Bastian Zimmer
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Explore the profile of Bastian Zimmer including associated specialties, affiliations and a list of published articles.
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23
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1068
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Recent Articles
1.
Zimmer B, Havenith R, Klein J, Koszinowski K
Angew Chem Int Ed Engl
. 2024 Jul;
63(44):e202409315.
PMID: 39072869
In recent years, the electronic structures of organocuprates in general and the complex [Cu(CF)] in particular have attracted significant interest. A possible key indicator in this context is the reactivity...
2.
Zimmer B, Auth T, Koszinowski K
Chemistry
. 2023 May;
29(41):e202300725.
PMID: 37139922
The cuprate complexes [Cu(R)(CF ) ] (R=organyl) offer an efficient synthetic access to valuable trifluoromethylation products RCF . Here, electrospray-ionization mass spectrometry is used to analyze the formation of these...
3.
Lafaille F, Harschnitz O, Lee Y, Zhang P, Hasek M, Kerner G, et al.
Nat Med
. 2019 Dec;
25(12):1873-1884.
PMID: 31806906
Herpes simplex virus-1 (HSV-1) encephalitis (HSE) is typically sporadic. Inborn errors of TLR3- and DBR1-mediated central nervous system cell-intrinsic immunity can account for forebrain and brainstem HSE, respectively. We report...
4.
Lipid Deprivation Induces a Stable, Naive-to-Primed Intermediate State of Pluripotency in Human PSCs
Cornacchia D, Zhang C, Zimmer B, Chung S, Fan Y, Soliman M, et al.
Cell Stem Cell
. 2019 Jun;
25(1):120-136.e10.
PMID: 31155483
Current challenges in capturing naive human pluripotent stem cells (hPSCs) suggest that the factors regulating human naive versus primed pluripotency remain incompletely defined. Here we demonstrate that the widely used...
5.
Kishinevsky S, Wang T, Rodina A, Chung S, Xu C, Philip J, et al.
Nat Commun
. 2018 Oct;
9(1):4345.
PMID: 30341316
Environmental and genetic risk factors contribute to Parkinson's Disease (PD) pathogenesis and the associated midbrain dopamine (mDA) neuron loss. Here, we identify early PD pathogenic events by developing methodology that...
6.
Zimmer B, Ewaleifoh O, Harschnitz O, Lee Y, Peneau C, McAlpine J, et al.
Proc Natl Acad Sci U S A
. 2018 Aug;
115(37):E8775-E8782.
PMID: 30154162
Herpes simplex virus type 1 (HSV-1) encephalitis (HSE) is the most common sporadic viral encephalitis in Western countries. Some HSE children carry inborn errors of the Toll-like receptor 3 (TLR3)-dependent...
7.
Zhang S, Clark N, Freije C, Pauwels E, Taggart A, Okada S, et al.
Cell
. 2018 Feb;
172(5):952-965.e18.
PMID: 29474921
Viruses that are typically benign sometimes invade the brainstem in otherwise healthy children. We report bi-allelic DBR1 mutations in unrelated patients from different ethnicities, each of whom had brainstem infection...
8.
Tchieu J, Zimmer B, Fattahi F, Amin S, Zeltner N, Chen S, et al.
Cell Stem Cell
. 2017 Sep;
21(3):399-410.e7.
PMID: 28886367
Directing the fate of human pluripotent stem cells (hPSCs) into different lineages requires variable starting conditions and components with undefined activities, introducing inconsistencies that confound reproducibility and assessment of specific...
9.
Qi Y, Zhang X, Renier N, Wu Z, Atkin T, Sun Z, et al.
Nat Biotechnol
. 2017 Jan;
35(2):154-163.
PMID: 28112759
Considerable progress has been made in converting human pluripotent stem cells (hPSCs) into functional neurons. However, the protracted timing of human neuron specification and functional maturation remains a key challenge...
10.
Zeltner N, Fattahi F, Dubois N, Saurat N, Lafaille F, Shang L, et al.
Nat Med
. 2016 Nov;
22(12):1421-1427.
PMID: 27841875
Familial dysautonomia (FD) is a debilitating disorder that affects derivatives of the neural crest (NC). For unknown reasons, people with FD show marked differences in disease severity despite carrying an...