Nadja Zeltner
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Explore the profile of Nadja Zeltner including associated specialties, affiliations and a list of published articles.
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33
Citations
738
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Recent Articles
1.
Yun S, Chekuri A, Art J, Kondabolu K, Slaugenhaupt S, Zeltner N, et al.
bioRxiv
. 2024 Dec;
PMID: 39651221
Familial dysautonomia (FD) is a fatal autosomal recessive congenital neuropathy caused by a T-to-C mutation in intron 20 of the () gene, which causes tissue-specific skipping of exon 20 and...
2.
Saito-Diaz K, Saini T, Patel A, James C, Thomas K, Knight T, et al.
bioRxiv
. 2024 Nov;
PMID: 39605577
The extracellular matrix (ECM) is a mixture of glycoproteins and fibrous proteins that provide the biophysical properties necessary to maintain cellular homeostasis. ECM integrity is of particular importance during development,...
3.
Saito-Diaz K, Dietrich P, Saini T, Rashid M, Wu H, Ishan M, et al.
Sci Transl Med
. 2024 Nov;
16(774):eadq2418.
PMID: 39565876
The peripheral nervous system (PNS) is essential for proper body function. A high percentage of the world's population suffers from nerve degeneration or peripheral nerve damage. Despite this, there are...
4.
Wu H, Ishan M, Rashid M, Liu H, Zeltner N
Bio Protoc
. 2024 Nov;
14(21):e5101.
PMID: 39525966
The parasympathetic nervous system is essential for salivary gland development and functionality. Parasympathetic neuron (parasymN) innervation is the main neural network that controls salivary secretion. Therefore, an exclusive model to...
5.
Wu H, Hamilton C, Porritt H, Winbo A, Zeltner N
J Physiol
. 2024 Sep;
PMID: 39235952
Throughout our lifetime the heart executes cycles of contraction and relaxation to meet the body's ever-changing metabolic needs. This vital function is continuously regulated by the autonomic nervous system. Cardiovascular...
6.
Habecker B, Bers D, Birren S, Chang R, Herring N, Kay M, et al.
J Physiol
. 2024 May;
PMID: 38778747
This paper updates and builds on a previous White Paper in this journal that some of us contributed to concerning the molecular and cellular basis of cardiac neurobiology of heart...
7.
Wu H, Saito-Diaz K, Huang C, McAlpine J, Seo D, Magruder D, et al.
Cell Stem Cell
. 2024 Apr;
31(5):734-753.e8.
PMID: 38608707
Autonomic parasympathetic neurons (parasymNs) control unconscious body responses, including "rest-and-digest." ParasymN innervation is important for organ development, and parasymN dysfunction is a hallmark of autonomic neuropathy. However, parasymN function and...
8.
Zeltner N, Wu H, Saito-Diaz K, Sun X, Song M, Saini T, et al.
Res Sq
. 2024 Apr;
PMID: 38562819
The technology of human pluripotent stem cell (hPSC)-based 3D organoid/assembloid cultures has become a powerful tool for the study of human embryonic development, disease modeling and drug discovery in recent...
9.
Wu H, Art J, Saini T, Zeltner N
STAR Protoc
. 2024 Mar;
5(2):102970.
PMID: 38517897
Assessing the development and function of the sympathetic nervous system in diseases on a large scale is challenging. Here, we present a protocol to generate human pluripotent stem cell (hPSC)-derived...
10.
Dookwah M, Wagner S, Ishihara M, Yu S, Ulrichs H, Kulik M, et al.
Hum Mol Genet
. 2023 Sep;
32(24):3323-3341.
PMID: 37676252
GM3 Synthase Deficiency (GM3SD) is a neurodevelopmental disorder resulting from pathogenic variants in the ST3GAL5 gene, which encodes GM3 synthase, a glycosphingolipid (GSL)-specific sialyltransferase. This enzyme adds a sialic acid...