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Bastiaan T Heijmans

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Articles 138
Citations 8914
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Recent Articles
11.
Costeira R, Evangelista L, Wilson R, Yan X, Hellbach F, Sinke L, et al.
Clin Epigenetics . 2023 Oct; 15(1):166. PMID: 37858220
Background: B vitamins such as folate (B9), B6, and B12 are key in one carbon metabolism, which generates methyl donors for DNA methylation. Several studies have linked differential methylation to...
12.
Liu Y, Sinke L, Jonkman T, Slieker R, van Zwet E, Daxinger L, et al.
Clin Epigenetics . 2023 Aug; 15(1):135. PMID: 37626340
Background: Loss of epigenetic control is a hallmark of aging. Among the most prominent roles of epigenetic mechanisms is the inactivation of one of two copies of the X chromosome...
13.
Groene S, Gremmen I, van Zwet E, Roest A, Haak M, van Klink J, et al.
Eur J Endocrinol . 2023 Aug; 189(2):183-189. PMID: 37548178
Objective: Research suggests that postnatal catch-up growth after fetal growth restriction (FGR) occurs frequently. Yet, postnatal growth in singletons may be influenced by multiple factors. Identical twins with discordant prenatal...
14.
Todtenhaupt P, Franken L, Groene S, van Hoolwerff M, van der Meeren L, van Klink J, et al.
Cytotherapy . 2023 Jul; 25(10):1057-1068. PMID: 37516948
Background Aims: Human umbilical cord-derived mesenchymal stromal cells (hUC-MSCs) are increasingly used in research and therapy. To obtain hUC-MSCs, a diversity of isolation and expansion methods are applied. Here, we...
15.
Walton E, Baltramonaityte V, Calhoun V, Heijmans B, Thompson P, Cecil C
Mol Psychiatry . 2023 May; 28(7):2839-2847. PMID: 37185958
Epigenetic mechanisms, such as DNA methylation (DNAm), have gained increasing attention as potential biomarkers and mechanisms underlying risk for neurodevelopmental, psychiatric and other brain-based disorders. Yet, surprisingly little is known...
16.
Dekkers K, Slieker R, Ioan-Facsinay A, van Iterson M, Ikram M, van Greevenbroek M, et al.
Nat Commun . 2023 Feb; 14(1):544. PMID: 36725846
Immune cell function can be altered by lipids in circulation, a process potentially relevant to lipid-associated inflammatory diseases including atherosclerosis and rheumatoid arthritis. To gain further insight in the molecular...
17.
Hellbach F, Sinke L, Costeira R, Baumeister S, Beekman M, Louca P, et al.
Eur J Nutr . 2022 Dec; 62(3):1357-1375. PMID: 36571600
Purpose: Examining epigenetic patterns is a crucial step in identifying molecular changes of disease pathophysiology, with DNA methylation as the most accessible epigenetic measure. Diet is suggested to affect metabolism...
18.
Todtenhaupt P, van Pel M, Roest A, Heijmans B
Trends Endocrinol Metab . 2022 Jul; 33(9):614-627. PMID: 35902331
The intrauterine environment can induce alterations of the epigenome that have a lasting impact on disease risk. Current human studies in the field focus on a single epigenetic mark, DNA...
19.
Groene S, Stegmeijer K, Tan R, Steggerda S, Haak M, Slaghekke F, et al.
Lancet Child Adolesc Health . 2022 Jul; 6(9):624-632. PMID: 35871831
Background: Singletons born after fetal growth restriction (FGR) are at increased risk of poor neurodevelopmental outcomes. Studies of singletons with FGR usually compare outcomes with those without FGR, a comparison...
20.
Groene S, Openshaw K, Jansen-Storbacka L, Slaghekke F, Haak M, Heijmans B, et al.
Am J Obstet Gynecol . 2022 Jun; 227(5):755.e1-755.e10. PMID: 35667417
Background: In monochorionic twin pregnancies, the fetuses share a single placenta. When this placenta is unequally shared, a discordant antenatal growth pattern ensues resulting in high rates of perinatal morbidity...