Roderick C Slieker
Overview
Explore the profile of Roderick C Slieker including associated specialties, affiliations and a list of published articles.
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Articles
69
Citations
2832
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Recent Articles
1.
Abdulrahman Z, Slieker R, McGuire D, Welters M, van Poelgeest M, van der Burg S
J Immunother Cancer
. 2025 Mar;
13(3).
PMID: 40081939
Background: The tumor microenvironment (TME) is a complex and dynamic ecosystem that is known to influence responses to immunotherapy. We leveraged single-cell spatial transcriptomics to systematically dissect the intricate complexity...
2.
Naber A, Demus D, Slieker R, Nicolardi S, Beulens J, Elders P, et al.
Int J Mol Sci
. 2024 May;
25(10).
PMID: 38791405
Apolipoprotein-CIII (apo-CIII) inhibits the clearance of triglycerides from circulation and is associated with an increased risk of diabetes complications. It exists in four main proteoforms: O-glycosylated variants containing either zero,...
3.
Li X, Donnelly L, Slieker R, Beulens J, t Hart L, Elders P, et al.
Diabetologia
. 2024 Apr;
67(7):1343-1355.
PMID: 38625583
Aims/hypothesis: This study aimed to explore the added value of subgroups that categorise individuals with type 2 diabetes by k-means clustering for two primary care registries (the Netherlands and Scotland),...
4.
Slieker R, Warmerdam D, Vermeer M, van Doorn R, Heemskerk M, Scheeren F
Sci Rep
. 2024 Apr;
14(1):7966.
PMID: 38575727
The Major Histocompatibility Complex class I (MHC-I) system plays a vital role in immune responses by presenting antigens to T cells. Allele specific technologies, including recombinant MHC-I technologies, have been...
5.
Li S, Dragan I, Tran V, Fung C, Kuznetsov D, Hansen M, et al.
Front Endocrinol (Lausanne)
. 2024 Mar;
15:1350796.
PMID: 38510703
Introduction: Type 2 diabetes (T2D) onset, progression and outcomes differ substantially between individuals. Multi-omics analyses may allow a deeper understanding of these differences and ultimately facilitate personalised treatments. Here, in...
6.
Slieker R, Munch M, Donnelly L, Bouland G, Dragan I, Kuznetsov D, et al.
Diabetologia
. 2024 Feb;
67(5):885-894.
PMID: 38374450
Aims/hypothesis: People with type 2 diabetes are heterogeneous in their disease trajectory, with some progressing more quickly to insulin initiation than others. Although classical biomarkers such as age, HbA and...
7.
de Klerk J, Bijkerk R, Beulens J, van Zonneveld A, Muilwijk M, Harms P, et al.
Diabetes Obes Metab
. 2024 Feb;
26(5):1706-1713.
PMID: 38303102
Aim: To investigate the association of plasma metabolites with incident and prevalent chronic kidney disease (CKD) in people with type 2 diabetes and establish whether this association is causal. Materials...
8.
Oost L, Slieker R, Blom M, t Hart L, Hoenderop J, Beulens J, et al.
Genes Nutr
. 2024 Jan;
19(1):2.
PMID: 38279093
People with type 2 diabetes have a tenfold higher prevalence of hypomagnesemia, which is suggested to be caused by low dietary magnesium intake, medication use, and genetics. This study aims...
9.
de Groot D, Linders L, Kayser R, Nederlof R, de Esch C, Slieker R, et al.
Toxicol Mech Methods
. 2023 Nov;
34(3):283-299.
PMID: 37946400
Disruption of the immune system during embryonic brain development by environmental chemicals was proposed as a possible cause of neurodevelopmental disorders. We previously found adverse effects of di-n-octyltin dichloride (DOTC)...
10.
Liu Y, Sinke L, Jonkman T, Slieker R, van Zwet E, Daxinger L, et al.
Clin Epigenetics
. 2023 Aug;
15(1):135.
PMID: 37626340
Background: Loss of epigenetic control is a hallmark of aging. Among the most prominent roles of epigenetic mechanisms is the inactivation of one of two copies of the X chromosome...