Bassel Akache
Overview
Explore the profile of Bassel Akache including associated specialties, affiliations and a list of published articles.
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Articles
41
Citations
1193
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Recent Articles
1.
Sanchez-Martinez Z, Alpuche-Lazcano S, Stuible M, Akache B, Renner T, Deschatelets L, et al.
Vaccine
. 2024 Oct;
42(26):126463.
PMID: 39481241
A vaccine effective against both SARS-CoV-2 and influenza A (IAV) viruses could represent a cost-effective strategy to reduce their combined public health burden as well as potential complications arising from...
2.
Akache B, McCluskie M
Hum Vaccin Immunother
. 2024 Sep;
20(1):2395081.
PMID: 39278862
Archaeosomes are liposomes traditionally comprised of total polar lipids or semi-synthetic glycerolipids of ether-linked isoprenoid phytanyl cores with varied glycol- and amino-head groups. We have developed a semi-synthetic archaeosome formulation...
3.
Agbayani G, Akache B, Renner T, Tran A, Stuible M, Dudani R, et al.
Eur J Immunol
. 2024 Apr;
54(6):e2350620.
PMID: 38561974
With the continued transmission of SARS-CoV-2 across widely vaccinated populations, it remains important to develop new vaccines and vaccination strategies capable of providing protective immunity and limiting the spread of...
4.
Beitari S, Agbayani G, Hewitt M, Duque D, Bavananthasivam J, Sandhu J, et al.
Sci Rep
. 2023 Dec;
13(1):21390.
PMID: 38049498
A critical feature of the VSV vector platform is the ability to pseudotype the virus with different glycoproteins from other viruses, thus altering cellular tropism of the recombinant virus. The...
5.
Gashti A, Agbayani G, Hrapovic S, Nassoury N, Coulombe N, Dudani R, et al.
Vaccine
. 2023 Dec;
42(1):40-52.
PMID: 38042697
The virus-like particle (VLP) platform is a robust inducer of humoral and cellular immune responses; hence, it has been used in vaccine development for several infectious diseases. In the current...
6.
Alpuche-Lazcano S, Stuible M, Akache B, Tran A, Kelly J, Hrapovic S, et al.
Commun Med (Lond)
. 2023 Aug;
3(1):116.
PMID: 37612423
Background: As the COVID-19 pandemic continues to evolve, novel vaccines need to be developed that are readily manufacturable and provide clinical efficacy against emerging SARS-CoV-2 variants. Virus-like particles (VLPs) presenting...
7.
Akache B, Read A, Dudani R, Harrison B, Williams D, Deschatelets L, et al.
Vaccines (Basel)
. 2023 Jun;
11(6).
PMID: 37376432
Vaccines play an important role in maintaining human and animal health worldwide. There is continued demand for effective and safe adjuvants capable of enhancing antigen-specific responses to a target pathogen....
8.
Renner T, Akache B, Stuible M, Rohani N, Cepero-Donates Y, Deschatelets L, et al.
Front Immunol
. 2023 May;
14:1182556.
PMID: 37122746
Liposomes composed of sulfated lactosyl archaeol (SLA) have been shown to be a safe and effective vaccine adjuvant with a multitude of antigens in preclinical studies. In particular, SLA-adjuvanted SARS-CoV-2...
9.
Maltseva M, Galipeau Y, Renner T, Deschatelets L, Durocher Y, Akache B, et al.
Vaccines (Basel)
. 2023 Jan;
11(1).
PMID: 36679875
Continuous viral evolution of SARS-CoV-2 has resulted in variants capable of immune evasion, vaccine breakthrough infections and increased transmissibility. New vaccines that invoke mucosal immunity may provide a solution to...
10.
Renner T, Agbayani G, Dudani R, McCluskie M, Akache B
Biomedicines
. 2023 Jan;
11(1).
PMID: 36672648
Inflammatory bowel disease (IBD) is a chronic ailment afflicting millions of people worldwide, with the majority of recognized cases within industrialized countries. The impacts of IBD at the individual level...