Basheer Becerra
Overview
Explore the profile of Basheer Becerra including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
56
Followers
0
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Recent Articles
1.
Becerra B, Wittibschlager S, Patel Z, Kutschat A, Delano J, Che E, et al.
bioRxiv
. 2024 Sep;
PMID: 39314441
CRISPR tiling screens have advanced the identification and characterization of regulatory sequences but are limited by low resolution arising from the indirect readout of editing via guide RNA sequencing. This...
2.
Sreekanth V, Jan M, Zhao K, Lim D, Davis J, McConkey M, et al.
bioRxiv
. 2023 Mar;
PMID: 36945568
Cas9 is a programmable nuclease that has furnished transformative technologies, including base editors and transcription modulators (e.g., CRISPRi/a), but several applications of these technologies, including therapeutics, mandatorily require precision control...
3.
Rube H, Rastogi C, Feng S, Kribelbauer J, Li A, Becerra B, et al.
Nat Biotechnol
. 2022 May;
40(10):1520-1527.
PMID: 35606422
Protein-ligand interactions are increasingly profiled at high throughput using affinity selection and massively parallel sequencing. However, these assays do not provide the biophysical parameters that most rigorously quantify molecular interactions....
4.
Ganz J, Maury E, Becerra B, Bizzotto S, Doan R, Kenny C, et al.
Cancer Discov
. 2021 Aug;
12(1):172-185.
PMID: 34389641
Although oncogenic mutations have been found in nondiseased, proliferative nonneural tissues, their prevalence in the human brain is unknown. Targeted sequencing of genes implicated in brain tumors in 418 samples...