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Bart Vanderborght

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Articles 25
Citations 572
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Recent Articles
1.
Bigio B, Lima-Filho R, Barnhill O, Sudo F, Drummond C, Assuncao N, et al.
Mol Psychiatry . 2025 Jan; PMID: 39774493
A major challenge in the development of more effective therapeutic strategies for Alzheimer's disease (AD) is the identification of molecular mechanisms linked to specific pathophysiological features of the disease. Importantly...
2.
De Muynck K, Heyerick L, De Ponti F, Vanderborght B, Meese T, Van Campenhout S, et al.
Hepatology . 2023 Aug; 79(2):269-288. PMID: 37535809
Background And Aims: Primary sclerosing cholangitis (PSC) is an immune-mediated cholestatic liver disease for which pharmacological treatment options are currently unavailable. PSC is strongly associated with colitis and a disruption...
3.
Gijbels E, De Muynck K, Vanderborght B, Meese T, Van Nieuwerburgh F, Vanlander A, et al.
Genes Dis . 2023 Apr; 10(1):18-21. PMID: 37013051
No abstract available.
4.
Vanderborght B, De Muynck K, Gijbels E, Lefere S, Scott C, Guilliams M, et al.
Int J Cancer . 2023 Mar; 152(12):2615-2628. PMID: 36912275
Due to a combination of rapid disease progression and the lack of curative treatment options, hepatocellular carcinoma (HCC) is one of the deadliest cancers worldwide. Infiltrated, monocyte-derived, tumor-associated macrophages are...
5.
De Muynck K, Vanderborght B, De Ponti F, Gijbels E, Van Welden S, Guilliams M, et al.
Am J Pathol . 2023 Jan; 193(4):366-379. PMID: 36642171
Primary sclerosing cholangitis (PSC) is an idiopathic chronic immune-mediated cholestatic liver disease characterized by fibro-inflammatory bile duct strictures, progressive hepatobiliary fibrosis, and gut-liver axis disruption. The pathophysiology of PSC remains...
6.
Goncalves R, Sudo F, Lourenco M, Drummond C, Assuncao N, Vanderborght B, et al.
Alzheimers Dement . 2022 Dec; 19(6):2595-2604. PMID: 36465055
Introduction: Depression is frequent among older adults and is a risk factor for dementia. Identifying molecular links between depression and dementia is necessary to shed light on shared disease mechanisms....
7.
Karmirian K, Holubiec M, Goto-Silva L, Bessone I, Vitoria G, Mello B, et al.
Methods Mol Biol . 2022 Nov; 2561:135-158. PMID: 36399268
Alzheimer's disease (AD) is the primary cause of dementia, to date. The urgent need to understand the biological and biochemical processes related to this condition, as well as the demand...
8.
Leroy K, Vilas-Boas V, Gijbels E, Vanderborght B, Devisscher L, Cogliati B, et al.
EXCLI J . 2022 Nov; 21:1111-1129. PMID: 36381643
Connexin proteins can form hexameric hemichannels and gap junctions that mediate paracrine and direct intercellular communication, respectively. Gap junction activity is crucial for the maintenance of hepatic homeostasis, while connexin...
9.
Pamplona F, Vitoria G, Sudo F, Ribeiro F, Isaac A, Moraes C, et al.
Transl Psychiatry . 2022 Oct; 12(1):439. PMID: 36216800
Age increases the risk for cognitive impairment and is the single major risk factor for Alzheimer's disease (AD), the most prevalent form of dementia in the elderly. The pathophysiological processes...
10.
Guilliams M, Bonnardel J, Haest B, Vanderborght B, Wagner C, Remmerie A, et al.
Cell . 2022 Jan; 185(2):379-396.e38. PMID: 35021063
The liver is the largest solid organ in the body, yet it remains incompletely characterized. Here we present a spatial proteogenomic atlas of the healthy and obese human and murine...