Barry J Thompson
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Explore the profile of Barry J Thompson including associated specialties, affiliations and a list of published articles.
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49
Citations
2316
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Recent Articles
1.
Bonello T, Cai D, Fletcher G, Wiengartner K, Pengilly V, Lange K, et al.
EMBO J
. 2023 Feb;
42(6):e112863.
PMID: 36807601
The Hippo pathway was originally discovered to control tissue growth in Drosophila and includes the Hippo kinase (Hpo; MST1/2 in mammals), scaffold protein Salvador (Sav; SAV1 in mammals) and the...
2.
Bonello T, Aguilar-Aragon M, Tournier A, Thompson B, Campanale J
Cells Dev
. 2021 Jul;
168:203719.
PMID: 34242843
Adherens junctions are a defining feature of all epithelial cells, providing cell-cell adhesion and contractile ring formation that is essential for cell and tissue morphology. In Drosophila, adherens junctions are...
3.
Leach J, Vlahov N, Tsantoulis P, Ridgway R, Flanagan D, Gilroy K, et al.
Nat Commun
. 2021 Jun;
12(1):3464.
PMID: 34103493
Right-sided (proximal) colorectal cancer (CRC) has a poor prognosis and a distinct mutational profile, characterized by oncogenic BRAF mutations and aberrations in mismatch repair and TGFβ signalling. Here, we describe...
4.
Guillermin O, Angelis N, Sidor C, Ridgway R, Baulies A, Kucharska A, et al.
EMBO J
. 2021 May;
40(13):e105770.
PMID: 33950519
Wnt signalling induces a gradient of stem/progenitor cell proliferation along the crypt-villus axis of the intestine, which becomes expanded during intestinal regeneration or tumour formation. The YAP transcriptional co-activator is...
5.
Thompson B
FEBS J
. 2021 Feb;
289(3):596-613.
PMID: 33565714
The Par-3/Baz family of polarity determinants is highly conserved across metazoans and includes C. elegans PAR-3, Drosophila Bazooka (Baz), human Par-3 (PARD3), and human Par-3-like (PARD3B). The C. elegans PAR-3...
6.
Thompson B
Curr Opin Insect Sci
. 2020 Sep;
43:1-10.
PMID: 32898719
Metamorphosis (Greek for a state of transcending-form or change-in-shape) refers to a dramatic transformation of an animal's body structure that occurs after development of the embryo or larva in many...
7.
Thompson B
Bioessays
. 2020 Mar;
42(5):e1900162.
PMID: 32128850
The transcriptional co-activators YAP (or YAP1) and TAZ (or WWTR1) are frequently activated during the growth and progression of many solid tumors, including lung, colorectal, breast, pancreatic, and liver carcinomas...
8.
Diaz-de-la-Loza M, Loker R, Mann R, Thompson B
Development
. 2020 Mar;
147(5).
PMID: 32122911
Mutations in the () gene cause homeotic transformation of the normally two-winged into a four-winged mutant fly. encodes a HOX family transcription factor that specifies segment identity, including transformation of...
9.
Aguilar-Aragon M, Bonello T, Bell G, Fletcher G, Thompson B
EMBO Rep
. 2020 Feb;
21(4):e49700.
PMID: 32030856
Epithelial cells undergo cortical rounding at the onset of mitosis to enable spindle orientation in the plane of the epithelium. In cuboidal epithelia in culture, the adherens junction protein E-cadherin...
10.
Sidor C, Borreguero-Munoz N, Fletcher G, Elbediwy A, Guillermin O, Thompson B
Elife
. 2019 Oct;
8.
PMID: 31661072
Mask family proteins were discovered in to promote the activity of the transcriptional coactivator Yorkie (Yki), the sole fly homolog of mammalian YAP (YAP1) and TAZ (WWTR1). The molecular function...