Barbara Klajnert-Maculewicz
Overview
Explore the profile of Barbara Klajnert-Maculewicz including associated specialties, affiliations and a list of published articles.
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65
Citations
716
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Recent Articles
1.
Gosecka M, Jaworska-Krych D, Gosecki M, Urbaniak M, Wielgus E, Gostynski B, et al.
ACS Appl Mater Interfaces
. 2025 Feb;
17(9):13427-13444.
PMID: 39982379
The severe side effects of systemic chemotherapy for cervical cancer encourage the use of topical intravaginal drug delivery systems. 5-fluorouracil, 5-FU, is an anticancer drug accepted in clinical use in...
2.
Mullerova M, Tarach P, Strasak T, Curinova P, Petrickovic R, Zavodna T, et al.
ACS Omega
. 2025 Jan;
10(1):1047-1060.
PMID: 39829590
Efficient and safe carriers of genetic material are crucial for advancing gene therapy. Three new series of cationic dendritic nanocarriers based on a carbosilane scaffold, differentiated by peripheral modifications: saccharide...
3.
Hansen C, Janaszewska A, Dabrzalska M, Marcinkowska M, Klajnert-Maculewicz B, Christensen J
RSC Adv
. 2024 Sep;
14(39):28684-28692.
PMID: 39257659
A series of 6 small PAMAM dendrimers (G0-dendrimers) differing in the size, polarity and flexibility has been synthesized. The toxicity has been investigated in three different human cancer cell lines...
4.
Gosecka M, Gosecki M, Ziemczonek P, Urbaniak M, Wielgus E, Marcinkowska M, et al.
ACS Appl Mater Interfaces
. 2024 Mar;
16(12):14605-14625.
PMID: 38488848
In the face of severe side effects of systemic chemotherapy used in cervical cancer, topical selective drug carriers with long-lasting effects are being sought. Hydrogels are suitable platforms, but their...
5.
Klajnert-Maculewicz B, Janaszewska A, Majecka A
Chem Commun (Camb)
. 2023 Nov;
59(99):14611-14625.
PMID: 37999927
In recent years, dendrimer-based vesicles, known as dendrimersomes, have garnered significant attention as highly promising alternatives to lipid vesicles in a variety of biomedical applications. Dendrimersomes offer several advantages, including...
6.
Firdaus S, Boye S, Janke A, Friedel P, Janaszewska A, Appelhans D, et al.
Biomacromolecules
. 2023 Nov;
24(12):5797-5806.
PMID: 37939018
Amyloid β peptide can aggregate into thin β-sheet fibrils or plaques deposited on the extracellular matrix, which is the hallmark of Alzheimer's disease. Multifunctional macromolecular structures play an important role...
7.
Piorecka K, Kurjata J, Gostynski B, Kazmierski S, Stanczyk W, Marcinkowska M, et al.
RSC Adv
. 2023 Jul;
13(31):21421-21431.
PMID: 37465576
Cancer is a global health problem being the second worldwide cause of deaths right after cardiovascular diseases. The main methods of cancer treatment involve surgery, radiation and chemotherapy with an...
8.
Gorzkiewicz M, Marcinkowska M, Studzian M, Karwaciak I, Pulaski L, Klajnert-Maculewicz B
Int J Nanomedicine
. 2023 May;
18:2109-2126.
PMID: 37122501
Background: Mesalazine is one of the main drugs used to treat inflammatory bowel diseases. However, its applicability is limited by its rapid inactivation and removal from the organism, as well...
9.
Gosecki M, Ziemczonek P, Gosecka M, Urbaniak M, Wielgus E, Marcinkowska M, et al.
J Mater Chem B
. 2023 Mar;
11(24):5552-5564.
PMID: 36877094
Clotrimazole, a hydrophobic drug routinely used in the treatment of vaginal candidiasis, also shows antitumor activity. However, its use in chemotherapy has been unsuccessful to date due to its low...
10.
Gosecka M, Jaworska-Krych D, Gosecki M, Wielgus E, Marcinkowska M, Janaszewska A, et al.
Biomacromolecules
. 2022 Sep;
23(10):4203-4219.
PMID: 36073031
Injectable, self-healing hydrogels with enhanced solubilization of hydrophobic drugs are urgently needed for antimicrobial intravaginal therapies. Here, we report the first hydrogel systems constructed of dynamic boronic esters cross-linking unimolecular...