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Barbara Costa

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Articles 188
Citations 3410
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Recent Articles
1.
Jesus J, Regadas J, Costa B, Carvalho J, Padua A, Henriques C, et al.
Pharmaceutics . 2025 Jan; 16(12. PMID: 39771557
Background/objectives: The unique properties of iron oxide nanoparticles have attracted significant interest within the biomedical community, particularly for magnetic hyperthermia applications. Various synthesis methods have been developed to optimize these...
2.
Costa B, Gouveia M, Vale N
Antioxidants (Basel) . 2025 Jan; 13(12. PMID: 39765846
Oxidative stress plays a critical role in various physiological and pathological processes, particularly during pregnancy, where it can significantly affect maternal and fetal health. In the context of viral infections,...
3.
Germelli L, Angeloni E, Da Pozzo E, Tremolanti C, De Felice M, Giacomelli C, et al.
Cell Mol Life Sci . 2025 Jan; 82(1):34. PMID: 39757281
An aberrant pro-inflammatory microglia response has been associated with most neurodegenerative disorders. Identifying microglia druggable checkpoints to restore their physiological functions is an emerging challenge. Recent data have shown that...
4.
Costa B, Pascoal D, Sousa R, Ricardo R, Figueiredo A
Cureus . 2025 Jan; 16(12):e74982. PMID: 39744291
Advances in implants and biological therapies have significantly improved trauma care, offering surgeons a variety of solutions for complex cases. This study evaluates the outcomes of three patients with complex...
5.
Angeloni E, Germelli L, Costa B, Martini C, Da Pozzo E
Neurochem Int . 2024 Dec; 182():105916. PMID: 39681140
Neurosteroids have a crucial role in physiological intrinsic regulations of the Central Nervous System functions. They are derived from peripheral steroidogenic sources and from the de novo neurosteroidogenic capacity of...
6.
Poggetti V, Angeloni E, Germelli L, Natale B, Waqas M, Sarno G, et al.
ACS Chem Neurosci . 2024 Nov; 16(1):1-15. PMID: 39545683
In searching for putative new therapeutic strategies to treat neurodegenerative diseases, the mitochondrial 18 kDa translocator protein (TSPO) and cerebral isoforms of carbonic anhydrase (CA) were exploited as potential targets....
7.
Chelucci E, Scarfo G, Piccarducci R, Rizza A, Fusi J, Epifani F, et al.
J Mol Neurosci . 2024 Nov; 74(4):105. PMID: 39496982
Physical activity has been demonstrated to improve cognitive function, thereby preventing/slowing neurodegenerative diseases (NDs). Biological responses to physical activity and vulnerabilities to NDs are emerging to be gender-related. Herein, known...
8.
Costa B, Gouveia M, Vale N
Pharmaceutics . 2024 Sep; 16(9). PMID: 39339201
This study aimed to model the pharmacokinetics of lamotrigine (LTG) and efavirenz (EFV) in pregnant women using physiologically based pharmacokinetic (PBPK) and pregnancy-specific PBPK (p-PBPK) models. For lamotrigine, the adult...
9.
Costa B, Vale N
J Clin Med . 2024 Aug; 13(15). PMID: 39124665
Advancements in psychotropic therapy for pregnant women are pivotal for addressing maternal mental health during the perinatal period. Screening for mood and anxiety symptoms during pregnancy is recommended to enable...
10.
Costa B, Gouveia M, Vale N
Vaccines (Basel) . 2024 Jul; 12(7). PMID: 39066420
Addressing the complexities of managing viral infections during pregnancy is essential for informed medical decision-making. This comprehensive review delves into the management of key viral infections impacting pregnant women, namely...