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B R Rifkin

Explore the profile of B R Rifkin including associated specialties, affiliations and a list of published articles. Areas
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Articles 38
Citations 361
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Recent Articles
1.
Llavaneras A, Ramamurthy N, Heikkila P, Teronen O, Salo T, Rifkin B, et al.
J Periodontol . 2001 Aug; 72(8):1069-77. PMID: 11525440
Background: Chemically modified non-antimicrobial tetracyclines (CMTs) have been shown to inhibit pathologically elevated collagenase (and other matrix metalloproteinase, MMP) activity and bone resorption in vivo and in vitro. Methods: In...
2.
Liu Y, Ramamurthy N, Marecek J, Lee H, Chen J, Ryan M, et al.
Curr Med Chem . 2001 Feb; 8(3):243-52. PMID: 11172678
CMTs are analogs of tetracyclines, which are chemically modified to eliminate their antimicrobial efficacy but which retain their inhibitory activity against matrix metalloproteinases. These compounds have been found to inhibit...
3.
Llavaneras A, Golub L, Rifkin B, Heikkila P, Sorsa T, Teronen O, et al.
Ann N Y Acad Sci . 1999 Jul; 878:671-4. PMID: 10415804
No abstract available.
4.
Vernillo A, Rifkin B
Adv Dent Res . 1999 Feb; 12(2):56-62. PMID: 9972123
The anti-resorptive properties of tetracyclines (TCs) and their non-antimicrobial, chemically modified analogues (CMTs) have enormous therapeutic potential in medicine and dentistry. Osseous destructive diseases associated with excessive mammalian collagenase (matrix...
5.
Sorsa T, Ramamurthy N, Vernillo A, Zhang X, Konttinen Y, Rifkin B, et al.
J Rheumatol . 1998 May; 25(5):975-82. PMID: 9598901
Objective: We studied the relative ability of 6 different chemically modified non-antimicrobial analogs of tetracycline (CMT) to inhibit human and chicken matrix metalloproteinases (MMP) in vitro. The ability of tetracycline...
6.
Spielman A, Bivona P, Rifkin B
N Y State Dent J . 1996 Dec; 62(10):36-42. PMID: 9002736
Halitosis is caused primarily by bacterial putrefaction and the generation of volatile sulfur compounds. Ninety percent of patients suffering from halitosis have oral causes, such as poor oral hygiene, periodontal...
7.
Zaidi M, Shankar V, Adebanjo O, Lai F, Pazianas M, Sunavala G, et al.
Am J Physiol . 1996 Sep; 271(3 Pt 2):F637-44. PMID: 8853426
Certain eukaryotic cells can sense changes in their extracellular Ca2+ concentration through molecular structures termed Ca(2+)-sensing receptors (CaRs). We have shown recently that in the bone-resorbing osteoclast, a unique cell...
8.
Zaidi M, Shankar V, Tunwell R, Adebanjo O, Mackrill J, Pazianas M, et al.
J Clin Invest . 1995 Sep; 96(3):1582-90. PMID: 7657829
Ryanodine receptors (RyRs) reside in microsomal membranes where they gate Ca2+ release in response to changes in the cytosolic Ca2+ concentration. In the osteoclast, a divalent cation sensor, the Ca2+...
9.
Debari K, Sasaki T, Udagawa N, Rifkin B
Calcif Tissue Int . 1995 Jun; 56(6):566-70. PMID: 7648488
This study was designed to evaluate the effects of specific and potent cathepsin inhibitors on osteoclastic resorptive functions in vitro by means of a novel ultrastructural assay system. Mouse bone...
10.
Rifkin B, Vernillo A, Golub L, Ramamurthy N
Ann N Y Acad Sci . 1994 Sep; 732:165-80. PMID: 7978789
No abstract available.