B R Ito
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Explore the profile of B R Ito including associated specialties, affiliations and a list of published articles.
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20
Citations
146
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Recent Articles
1.
Ito B, Zhang B, Cable E, Song X, Fujitaki J, MacKenna D, et al.
Br J Pharmacol
. 2009 Feb;
156(3):454-65.
PMID: 19183199
Background And Purpose: Thyroid hormone receptor (TR) agonists are in clinical trials for the treatment of hypercholesterolaemia. As statins are the standard of clinical care, any new therapies must have...
2.
Gu J, Ito B, Sartin A, Frascogna N, Moore M, Adair T
Am J Physiol Heart Circ Physiol
. 2000 Oct;
279(5):H2116-23.
PMID: 11045944
We tested whether increased endogenous adenosine produced by the adenosine kinase inhibitor GP-515 (Metabasis Therapeutics) can induce vascular endothelial growth factor (VEGF) expression in cultured rat myocardial myoblasts (RMMs). RMMs...
3.
Ito B
Circulation
. 1995 Apr;
91(7):2058-70.
PMID: 7895365
Background: With moderate reductions in coronary blood flow, adjustments in myocardial metabolism can occur with a normalization of the imbalance between the decreased O2 delivery and tissue O2 demand. This...
4.
Ito B, del Balzo U
Am J Physiol
. 1994 Oct;
267(4 Pt 2):H1288-94.
PMID: 7943373
Activation of the complement cascade is involved in the myocardial injury resulting from transient ischemia and reperfusion. We previously showed that the complement anaphylatoxin C5a causes myocardial ischemia in vivo,...
5.
Zimring H, Fitzgerald R, Engler R, Ito B
Circulation
. 1994 Apr;
89(4):1819-28.
PMID: 8149548
Background: Cocaine use has been associated with cardiomyopathy and ischemic coronary syndromes. However, the pathophysiological mechanisms responsible for these syndromes are not clear and have been suggested to involve direct...
6.
Juneau C, Ito B, del Balzo U, Engler R
Cardiovasc Res
. 1993 May;
27(5):720-7.
PMID: 8348569
Objective: The contribution of neutrophils to myocardial injury during stunning remains controversial because of conflicting results in neutropenic animals. The goal of this study was to compare the recovery of...
7.
Ito B, Engler R, del Balzo U
Am J Physiol
. 1993 May;
264(5 Pt 2):H1346-54.
PMID: 7684573
Activated complement component C5a causes myocardial ischemia mediated by thromboxane (Tx) A2 and leukotrienes C4/D4. Blood cells are not involved in either the mediator release or the myocardial effects of...
8.
del Balzo U, Engler R, Ito B
Am J Physiol
. 1993 Feb;
264(2 Pt 2):H336-44.
PMID: 8447449
The intracoronary infusion of complement C5a causes a decrease in coronary blood flow and contractile dysfunction mediated by thromboxane (TxA2) and leukotrienes. Although these effects are accompanied by polymorphonuclear leukocyte...
9.
Engler R, Roth D, del Balzo U, Ito B
FASEB J
. 1991 Nov;
5(14):2983-91.
PMID: 1661246
Activation of the complement cascade with the generation of anaphylatoxins accompanies the inflammatory response elicited by acute myocardial ischemia and reperfusion. Although complement is activated in the interstitium during acute...
10.
Ito B, Libraty D, Engler R
J Am Coll Cardiol
. 1991 Sep;
18(3):858-67.
PMID: 1869750
Myocardial ischemia of short duration (15 to 20 min) produces myocardial "stunning" during reperfusion. The vasoregulatory and contractile status of reperfused myocardium during normal and reduced perfusion pressures is of...