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E O FEIGL

Explore the profile of E O FEIGL including associated specialties, affiliations and a list of published articles. Areas
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Articles 80
Citations 1004
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Recent Articles
1.
Hamilton S, Hardouin S, Anagnostaras S, Murphy G, Richmond K, Silva A, et al.
Life Sci . 2001 Jun; 68(22-23):2489-93. PMID: 11392617
We used gene targeting to generate mice lacking the M1 muscarinic acetylcholine receptor. These mice exhibit a decreased susceptibility to pilocarpine-induced seizures, loss of regulation of M-current potassium channel activity...
2.
Tune J, Richmond K, Gorman M, FEIGL E
Am J Physiol Heart Circ Physiol . 2001 Feb; 280(2):H868-75. PMID: 11158988
The role of ATP-sensitive K(+) (K(ATP)(+)) channels, nitric oxide, and adenosine in coronary exercise hyperemia was investigated. Dogs (n = 10) were chronically instrumented with catheters in the aorta and...
3.
Gorman M, Tune J, Richmond K, FEIGL E
J Appl Physiol (1985) . 2000 Oct; 89(5):1903-11. PMID: 11053342
Recent experiments demonstrate that feedforward sympathetic beta-adrenoceptor coronary vasodilation occurs during exercise. The present study quantitatively examined the contributions of epinephrine and norepinephrine to exercise coronary hyperemia and tested the...
4.
Gorman M, Tune J, Richmond K, FEIGL E
J Appl Physiol (1985) . 2000 Oct; 89(5):1892-902. PMID: 11053341
The hypothesis that exercise-induced coronary vasodilation is a result of sympathetic activation of coronary smooth muscle beta-adrenoceptors was tested. Ten dogs were chronically instrumented with a flow transducer on the...
5.
Richmond K, Tune J, Gorman M, FEIGL E
J Appl Physiol (1985) . 2000 Aug; 89(2):529-36. PMID: 10926635
The present study was designed to examine the role of ATP-sensitive potassium (K(ATP)(+)) channels during exercise and to test the hypothesis that adenosine increases to compensate for the loss of...
6.
Tune J, Richmond K, Gorman M, FEIGL E
Circulation . 2000 Jun; 101(25):2942-8. PMID: 10869267
Background: Inhibition of nitric oxide (NO) synthesis results in very little change in coronary blood flow, but this is thought to be because cardiac adenosine concentration increases to compensate for...
7.
Tune J, Richmond K, Gorman M, Olsson R, FEIGL E
Am J Physiol Heart Circ Physiol . 2000 Jan; 278(1):H74-84. PMID: 10644586
The purpose of this investigation was to quantitatively evaluate the role of adenosine in coronary exercise hyperemia. Dogs (n = 10) were chronically instrumented with catheters in the aorta and...
8.
Richmond K, Tune J, Gorman M, FEIGL E
Am J Physiol . 1999 Dec; 277(6):H2115-23. PMID: 10600828
ATP-sensitive potassium (K+ATP) channels have been shown to play a role in the maintenance of basal coronary vascular tone in vivo. K+ATP channels are also involved in the coronary vasodilator...
9.
Yada T, Richmond K, Van Bibber R, Kroll K, FEIGL E
Am J Physiol . 1999 May; 276(5):H1425-33. PMID: 10330224
Adenosine has been postulated to mediate the increase in coronary blood flow when myocardial oxygen consumption is increased. The aim of this study was to evaluate the role of adenosine...
10.
FEIGL E
J Vasc Res . 1998 May; 35(2):85-92. PMID: 9588871
Parasympathetic control of coronary blood flow has been extensively studied in dogs, and a clear vasodilator effect not dependent on changes in myocardial metabolism was observed. Parasympathetic vasodilatation is mediated...