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B Lutterbach

Explore the profile of B Lutterbach including associated specialties, affiliations and a list of published articles. Areas
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Articles 18
Citations 906
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11.
Fenrick R, Amann J, Lutterbach B, Wang L, Westendorf J, Downing J, et al.
Mol Cell Biol . 1999 Sep; 19(10):6566-74. PMID: 10490596
t(12;21) is the most frequent translocation found in pediatric B-cell acute lymphoblastic leukemias. This translocation fuses a putative repressor domain from the TEL DNA-binding protein to nearly all of the...
12.
Lutterbach B, Hann S
J Cell Biochem . 1999 Feb; 72(4):483-91. PMID: 10022608
We have isolated and characterized cellular kinases which associate with the transactivation domain of c-Myc and phosphorylate Ser-62. We demonstrate that cellular Map kinases associate with c-Myc under stringent conditions...
13.
Lutterbach B, Westendorf J, Linggi B, Patten A, Moniwa M, Davie J, et al.
Mol Cell Biol . 1998 Nov; 18(12):7176-84. PMID: 9819404
t(8;21) is one of the most frequent translocations associated with acute myeloid leukemia. It produces a chimeric protein, acute myeloid leukemia-1 (AML-1)-eight-twenty-one (ETO), that contains the amino-terminal DNA binding domain...
14.
Lutterbach B, Sun D, Schuetz J, Hiebert S
Mol Cell Biol . 1998 Jun; 18(6):3604-11. PMID: 9584201
Chromosomal translocations in acute leukemia that affect the AML-1/CBFbeta transcription factor complex create dominant inhibitory proteins. However, the mechanisms by which these proteins act remain obscure. Here we demonstrate that...
15.
Lutterbach B, Hann S
Oncogene . 1997 Feb; 14(8):967-75. PMID: 9050996
Using an extensive series of deletion and site-specific mutation constructs, we have identified five new phosphorylation sites in c-Myc in the N-terminal transactivation domain and near the C-terminal DNA binding/heterodimerization...
16.
Hoang A, Lutterbach B, Lewis B, Yano T, Chou T, Barrett J, et al.
Mol Cell Biol . 1995 Aug; 15(8):4031-42. PMID: 7623799
The c-Myc protein is a transcription factor with an N-terminal transcriptional regulatory domain and C-terminal oligomerization and DNA-binding motifs. Previous studies have demonstrated that p107, a protein related to the...
17.
Lutterbach B, Hann S
Mol Cell Biol . 1994 Aug; 14(8):5510-22. PMID: 8035827
The N-terminal domain of the c-Myc protein has been reported to be critical for both the transactivation and biological functions of the c-Myc proteins. Through detailed phosphopeptide mapping analyses, we...
18.
Coulson A, Kozono Y, Lutterbach B, Shownkeen R, Sulston J, Waterston R
Bioessays . 1991 Aug; 13(8):413-7. PMID: 1953703
During the past decade, it has become apparent that it is within our grasp to understand fully the development and functioning of complex organisms. It is widely accepted that this...