B Lecka-Czernik
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Explore the profile of B Lecka-Czernik including associated specialties, affiliations and a list of published articles.
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20
Citations
990
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Recent Articles
1.
Ayyasamy R, Fan S, Czernik P, Lecka-Czernik B, Chattopadhyay S, Chakravarti R
J Biol Chem
. 2024 Jun;
300(7):107487.
PMID: 38908751
Macrophages are essential regulators of inflammation and bone loss. Receptor activator of nuclear factor-κβ ligand (RANKL), a pro-inflammatory cytokine, is responsible for macrophage differentiation to osteoclasts and bone loss. We...
2.
Stechschulte L, Czernik P, Rotter Z, Tausif F, Corzo C, Marciano D, et al.
EBioMedicine
. 2016 Jul;
10:174-84.
PMID: 27422345
The peroxisome proliferator-activated receptor gamma (PPARγ) regulates osteoblast and osteoclast differentiation, and is the molecular target of thiazolidinediones (TZDs), insulin sensitizers that enhance glucose utilization and adipocyte differentiation. However, clinical...
3.
Lecka-Czernik B, Stechschulte L, Czernik P, Dowling A
Mol Cell Endocrinol
. 2015 Jan;
410:35-41.
PMID: 25576855
Obesity is generally recognized as a condition which positively influences bone mass and bone mineral density (BMD). Positive effect of high body mass index (BMI) on bone has been recognized...
4.
Cheng Y, Rodriguiz R, Murthy S, Senatorov V, Thouennon E, Cawley N, et al.
Mol Psychiatry
. 2014 Oct;
20(6):744-54.
PMID: 25330741
Major depressive disorder is often linked to stress. Although short-term stress is without effect in mice, prolonged stress leads to depressive-like behavior, indicating that an allostatic mechanism exists in this...
5.
Krings A, Rahman S, Huang S, Lu Y, Czernik P, Lecka-Czernik B
Bone
. 2011 Jul;
50(2):546-52.
PMID: 21723971
Fat occupies a significant portion of bone cavity however its function is largely unknown. Marrow fat expands during aging and in conditions which affect energy metabolism, indicating that fat in...
6.
Huang S, Kaw M, Harris M, Ebraheim N, McInerney M, Najjar S, et al.
Bone
. 2010 Jan;
46(4):1138-45.
PMID: 20044046
Type 2 diabetes is associated with normal-to-higher bone mineral density (BMD) and increased rate of fracture. Hyperinsulinemia and hyperglycemia may affect bone mass and quality in the diabetic skeleton. In...
7.
Lecka-Czernik B
J Musculoskelet Neuronal Interact
. 2009 Jan;
8(4):346-7.
PMID: 19147970
No abstract available.
8.
Lecka-Czernik B
J Musculoskelet Neuronal Interact
. 2009 Jan;
8(4):344-5.
PMID: 19147969
No abstract available.
9.
Shockley K, Rosen C, Churchill G, Lecka-Czernik B
PPAR Res
. 2008 Feb;
2007:81219.
PMID: 18288266
Bone formation and hematopoiesis are anatomically juxtaposed and share common regulatory mechanisms. Bone marrow mesenchymal stromal/stem cells (MSC) contain a compartment that provides progeny with bone forming osteoblasts and fat...
10.
Lecka-Czernik B, Ackert-Bicknell C, Adamo M, Marmolejos V, Churchill G, Shockley K, et al.
Endocrinology
. 2006 Nov;
148(2):903-11.
PMID: 17122083
Rosiglitazone (Rosi) belongs to the class of thiazolidinediones (TZDs) that are ligands for peroxisome proliferator-activated receptor gamma (PPARgamma). Stimulation of PPARgamma suppresses bone formation and enhances marrow adipogenesis. We hypothesized...