B E Kemp
Overview
Explore the profile of B E Kemp including associated specialties, affiliations and a list of published articles.
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Articles
214
Citations
7139
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Recent Articles
1.
McAinch A, Steinberg G, Mollica J, OBrien P, Dixon J, Kemp B, et al.
Obes Res Clin Pract
. 2013 Dec;
1(1):1-78.
PMID: 24351431
Summary: Objective: To investigate the effects of leptin on the mRNA abundance of key genes involved in fatty acid oxidation and mitochondrial biogenesis in cultured skeletal muscle myotubes derived from...
2.
Beck Jorgensen S, ONeill H, Hewitt K, Kemp B, Steinberg G
Diabetologia
. 2009 Aug;
52(11):2395-404.
PMID: 19688337
Aims/hypothesis: Obesity-related insulin resistance is associated with accumulation of bioactive lipids in skeletal muscle. The AMP-activated protein kinase (AMPK) regulates lipid oxidation in muscle by inhibiting acetyl-CoA carboxylase-2 (ACC2) and...
3.
Oakhill J, Scott J, Kemp B
Acta Physiol (Oxf)
. 2009 Feb;
196(1):3-14.
PMID: 19245650
AMP-activated protein kinase (AMPK) regulates metabolism in response to energy demand and supply. AMPK is activated in response to rises in intracellular AMP or calcium-mediated signalling and is responsible for...
4.
Turpin S, Ryall J, Southgate R, Darby I, Hevener A, Febbraio M, et al.
J Physiol
. 2009 Feb;
587(Pt 7):1593-605.
PMID: 19204053
Excess lipid accumulation resulting from an elevated supply of plasma fatty acids is linked to the pathogenesis of the metabolic syndrome and heart disease. The term 'lipotoxicity' was coined to...
5.
McConell G, Manimmanakorn A, Lee-Young R, Kemp B, Linden K, Wadley G
J Appl Physiol (1985)
. 2008 Aug;
105(5):1422-7.
PMID: 18703760
Short-term exercise training in humans attenuates AMP-activated protein kinase (AMPK) activation during subsequent exercise conducted at the same absolute workload. Short-term 5-aminoimidazole-4-carboxyamide-ribonucleoside (AICAR) administration in rats mimics exercise training on...
6.
Wadley G, Lee-Young R, Canny B, Wasuntarawat C, Chen Z, Hargreaves M, et al.
Am J Physiol Endocrinol Metab
. 2005 Nov;
290(4):E694-702.
PMID: 16263768
We compared in human skeletal muscle the effect of absolute vs. relative exercise intensity on AMP-activated protein kinase (AMPK) signaling and substrate metabolism under normoxic and hypoxic conditions. Eight untrained...
7.
Ahmed N, Barker G, Oliva K, Hoffmann P, Riley C, Reeve S, et al.
Br J Cancer
. 2004 Jun;
91(1):129-40.
PMID: 15199385
Screening for specific biomarkers of early-stage detection of ovarian cancer is a major health priority due to the asymptomatic nature and poor survival characteristic of the disease. We utilised two-dimensional...
8.
Clark S, Chen Z, Murphy K, Aughey R, McKenna M, Kemp B, et al.
Am J Physiol Endocrinol Metab
. 2003 Dec;
286(5):E737-43.
PMID: 14693511
The AMP-activated protein kinase (AMPK) cascade has been linked to many of the acute effects of exercise on skeletal muscle substrate metabolism, as well as to some of the chronic...
9.
Kemp B, Stapleton D, Campbell D, Chen Z, Murthy S, Walter M, et al.
Biochem Soc Trans
. 2003 Jan;
31(Pt 1):162-8.
PMID: 12546677
The AMP-activated protein kinase (AMPK) is a metabolic-stress-sensing protein kinase that regulates metabolism in response to energy demand and supply by directly phosphorylating rate-limiting enzymes in metabolic pathways as well...
10.
Stephens T, Chen Z, Canny B, Michell B, Kemp B, McConell G
Am J Physiol Endocrinol Metab
. 2002 Feb;
282(3):E688-94.
PMID: 11832374
The effect of prolonged moderate-intensity exercise on human skeletal muscle AMP-activated protein kinase (AMPK)alpha1 and -alpha2 activity and acetyl-CoA carboxylase (ACCbeta) and neuronal nitric oxide synthase (nNOSmu) phosphorylation was investigated....