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B Chesebro

Explore the profile of B Chesebro including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 154
Citations 6369
Followers 0
Related Specialties
Allergy & Immunology
Microbiology
Science
Top 10 Co-Authors
K Wehrly
J Nishio
B Caughey
R E Race
S A Priola
R Race
K J Hasenkrug
M Miyazawa
S E Svehag
S Perryman
Published In
J Virol
J Exp Med
J Immunol
Virology
Proc Natl Acad Sci U S A
Affiliations
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Recent Articles
1.
Lack of influence of prion protein gene expression on kainate-induced seizures in mice: studies using congenic, coisogenic and transgenic strains
Striebel J, Race B, Pathmajeyan M, Rangel A, Chesebro B
Neuroscience . 2013 Feb; 238:11-8. PMID: 23415788
Prion protein (PrP) is a glycosylphosphatidylinositol (GPI) anchored cell surface protein expressed by many cells, including those of the mammalian nervous system. At present the physiologic functions of PrP remain...
2.
Non-amyloid and amyloid prion protein deposits in prion-infected mice differ in blockage of interstitial brain fluid
Rangel A, Race B, Striebel J, Chesebro B
Neuropathol Appl Neurobiol . 2012 Sep; 39(3):217-30. PMID: 22998478
Aims: Prion diseases are characterized by brain deposits of misfolded aggregated protease-resistant prion protein (PrP), termed PrPres. In humans and animals, PrPres is found as either disorganized non-amyloid aggregates or...
3.
Influence of proinflammatory cytokines and chemokines on the neuropathogenesis of oncornavirus and immunosuppressive lentivirus infections
Peterson K, Chesebro B
Curr Top Microbiol Immunol . 2006 Mar; 303:67-95. PMID: 16570857
Retroviral infection of the CNS can lead to severe debilitating neurological diseases in humans and other animals. Four general types of pathogenic effects with various retroviruses have been observed including:...
4.
A 6 week course of azithromycin treatment has no beneficial effect on atherosclerotic lesion development in apolipoprotein E-deficient mice chronically infected with Chlamydia pneumoniae
Blessing E, Campbell L, Rosenfeld M, Chesebro B, Kuo C
J Antimicrob Chemother . 2005 Apr; 55(6):1037-40. PMID: 15845780
Objectives: To evaluate whether antimicrobial chemotherapy prevents acceleration of atherosclerotic lesion development induced by infection with Chlamydia pneumoniae. Methods: ApoE-deficient mice which develop hyperlipidaemia and atherosclerosis spontaneously were inoculated intranasally...
5.
Long-term subclinical carrier state precedes scrapie replication and adaptation in a resistant species: analogies to bovine spongiform encephalopathy and variant Creutzfeldt-Jakob disease in humans
Race R, Raines A, Raymond G, Caughey B, Chesebro B
J Virol . 2001 Oct; 75(21):10106-12. PMID: 11581378
Cattle infected with bovine spongiform encephalopathy (BSE) appear to be a reservoir for transmission of variant Creutzfeldt-Jakob disease (vCJD) to humans. Although just over 100 people have developed clinical vCJD,...
6.
N-terminal truncation of prion protein affects both formation and conformation of abnormal protease-resistant prion protein generated in vitro
Lawson V, Priola S, Wehrly K, Chesebro B
J Biol Chem . 2001 Jul; 276(38):35265-71. PMID: 11466311
Transmissible spongiform encephalopathy diseases are characterized by conversion of the normal protease-sensitive host prion protein, PrP-sen, to an abnormal protease-resistant form, PrP-res. In the current study, deletions were introduced into...
7.
Transmissible spongiform encephalopathies and prion protein interconversions
Caughey B, Chesebro B
Adv Virus Res . 2001 Jul; 56:277-311. PMID: 11450303
No abstract available.
8.
Differences in cytokine and chemokine responses during neurological disease induced by polytropic murine retroviruses Map to separate regions of the viral envelope gene
Peterson K, Robertson S, Portis J, Chesebro B
J Virol . 2001 Feb; 75(6):2848-56. PMID: 11222710
Infection of the central nervous system (CNS) by several viruses can lead to upregulation of proinflammatory cytokines and chemokines. In immunocompetent adults, these molecules induce prominent inflammatory infiltrates. However, with...
9.
Inhibition of formation of protease-resistant prion protein by Trypan Blue, Sirius Red and other Congo Red analogs
Demaimay R, Chesebro B, Caughey B
Arch Virol Suppl . 2001 Feb; (16):277-83. PMID: 11214931
Five compounds related to Congo Red were found to inhibit generation of protease-resistant prion protein in a cell-free system. In this assay Trypan Blue, Evans Blue, Sirius Red F3B, Primuline...
10.
Sulfated glycans and elevated temperature stimulate PrP(Sc)-dependent cell-free formation of protease-resistant prion protein
Wong C, Xiong L, Horiuchi M, Raymond L, Wehrly K, Chesebro B, et al.
EMBO J . 2001 Feb; 20(3):377-86. PMID: 11157745
A conformational conversion of the normal, protease- sensitive prion protein (PrP-sen or PrP(C)) to a protease-resistant form (PrP-res or PrP(Sc)) is commonly thought to be required in transmissible spongiform encephalopathies...