B Brugger
Overview
Explore the profile of B Brugger including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
866
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Recent Articles
1.
Targeting myelin lipid metabolism as a potential therapeutic strategy in a model of CMT1A neuropathy
Fledrich R, Abdelaal T, Rasch L, Bansal V, Schutza V, Brugger B, et al.
Nat Commun
. 2018 Aug;
9(1):3025.
PMID: 30072689
In patients with Charcot-Marie-Tooth disease 1A (CMT1A), peripheral nerves display aberrant myelination during postnatal development, followed by slowly progressive demyelination and axonal loss during adult life. Here, we show that...
2.
Paumet F, Brugger B, Parlati F, McNew J, Sollner T, Rothman J
J Cell Biol
. 2001 Dec;
155(6):961-8.
PMID: 11739407
The t-SNARE in a late Golgi compartment (Tlg2p) syntaxin is required for endocytosis and localization of cycling proteins to the late Golgi compartment in yeast. We show here that Tlg2p...
3.
Gkantiragas I, Brugger B, Stuven E, Kaloyanova D, Li X, LOHR K, et al.
Mol Biol Cell
. 2001 Jun;
12(6):1819-33.
PMID: 11408588
Sphingomyelin- and cholesterol-enriched microdomains can be isolated as detergent-resistant membranes from total cell extracts (total-DRM). It is generally believed that this total-DRM represents microdomains of the plasma membrane. Here we...
4.
Brugger B, Sandhoff R, Wegehingel S, Gorgas K, Malsam J, Helms J, et al.
J Cell Biol
. 2000 Nov;
151(3):507-18.
PMID: 11062253
In higher eukaryotes, phospholipid and cholesterol synthesis occurs mainly in the endoplasmic reticulum, whereas sphingomyelin and higher glycosphingolipids are synthesized in the Golgi apparatus. Lipids like cholesterol and sphingomyelin are...
5.
Volchuk A, Amherdt M, Ravazzola M, Brugger B, Rivera V, Clackson T, et al.
Cell
. 2000 Sep;
102(3):335-48.
PMID: 10975524
Engineered protein aggregates ranging up to 400 nm in diameter were selectively deposited within the cis-most cisternae of the Golgi stack following a 15 degrees C block. These aggregates are...
6.
Brugger B, Nickel W, Weber T, Parlati F, McNew J, Rothman J, et al.
EMBO J
. 2000 Mar;
19(6):1272-8.
PMID: 10716927
It has recently been reported that N-ethylmaleimide-sensitive fusion ATPase (NSF) can fuse protein-free liposomes containing substantial amounts of 1,2-dioleoylphosphatidylserine (DOPS) and 1, 2-dioleoyl-phosphatidyl-ethanolamine (DOPE) (Otter-Nilsson et al., 1999). The authors...
7.
SCHNEITER R, Brugger B, Sandhoff R, Zellnig G, Leber A, Lampl M, et al.
J Cell Biol
. 1999 Aug;
146(4):741-54.
PMID: 10459010
Nano-electrospray ionization tandem mass spectrometry (nano-ESI-MS/MS) was employed to determine qualitative differences in the lipid molecular species composition of a comprehensive set of organellar membranes, isolated from a single culture...
8.
Ledesma M, Brugger B, Bunning C, Wieland F, Dotti C
EMBO J
. 1999 Apr;
18(7):1761-71.
PMID: 10202140
Neuronal maturation is a gradual process; first axons and dendrites are established as distinct morphological entities; next the different intracellular organization of these processes occurs; and finally the specialized plasma...
9.
Reinhard C, Harter C, Bremser M, Brugger B, Sohn K, Helms J, et al.
Proc Natl Acad Sci U S A
. 1999 Feb;
96(4):1224-8.
PMID: 9990005
Coatomer, the coat protein complex of COPI vesicles, is involved in the budding of these vesicles, but the underlying mechanism is unknown. Toward a better understanding of this process, the...
10.
Sandhoff R, Brugger B, JECKEL D, Lehmann W, Wieland F
J Lipid Res
. 1998 Dec;
40(1):126-32.
PMID: 9869658
A mass spectrometric method for the quantification of free cholesterol in cells and subcellular membranes is presented. The method is based on a simple one-step chemical derivatization of cholesterol to...