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B Brandts

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Articles 18
Citations 130
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Recent Articles
1.
Brandts B, Dirkmann D, Borchard R, Wickenbrock I, Van Bracht M, Prull M, et al.
Z Kardiol . 2004 Jul; 93(7):533-9. PMID: 15243764
Objectives: Betablocking agents are known to exert anti-arrhythmic effects in ischemic myocardium due to blockade of myocardial beta-1-receptors. Since adenosine (Ado) induced muscarinic potassium current (IK(Ado)) and ATP sensitive potassium...
2.
Brandts B, Borchard R, Macianskiene R, Gendviliene V, Dirkmann D, Van Bracht M, et al.
J Pharmacol Exp Ther . 2003 Oct; 308(1):134-42. PMID: 14569071
2-Methyl-3- (3,5-diiodo-4-carboxymethoxybenzyl) benzofuran (KB130015; KB), a novel compound derived from amiodarone, has been proposed to have antiarrhythmic properties. Its effect on the G protein-coupled inward rectifying K+ current [IK(ACh) or...
3.
Macianskiene R, Bito V, Raeymaekers L, Brandts B, Sipido K, Mubagwa K
Br J Pharmacol . 2003 Aug; 139(8):1469-79. PMID: 12922934
1. We have studied the acute cardiac electrophysiological effects of KB130015 (KB), a drug structurally related to amiodarone. Membrane currents and action potentials were measured at room temperature or at...
4.
Brandts B, Borchard R, Dirkmann D, Wickenbrock I, Sievers B, Van Bracht M, et al.
Br J Pharmacol . 2003 Aug; 139(7):1265-72. PMID: 12890705
(1) Diadenosine polyphosphates have been described to be present in the myocardium and exert purinergic- and nonreceptor-mediated effects. Since the electrophysiological properties of atrial myocardium are effectively regulated by A(1)...
5.
Sievers B, Prull M, Brandts B, Horstmann E, Ranke C, Trappe H
Internist (Berl) . 2003 Apr; 44(1):88-93. PMID: 12677710
No abstract available.
6.
Weismuller P, Kratz C, Brandts B, Kattenbeck K, Trappe H, Ranke C
Ann Noninvasive Electrocardiol . 2001 Nov; 6(4):285-9. PMID: 11686908
Background: Patients with more than one AV nodal pathway show two and more peaks in the histogram of the R-R intervals of the Holter monitoring ECG during atrial fibrillation. It...
7.
Liliom K, Sun G, Bunemann M, Virag T, Nusser N, Baker D, et al.
Biochem J . 2001 Mar; 355(Pt 1):189-97. PMID: 11256963
Blood plasma and serum contain factors that activate inwardly rectifying GIRK1/GIRK4 K+ channels in atrial myocytes via one or more non-atropine-sensitive receptors coupled to pertussis-toxin-sensitive G-proteins. This channel is also...
8.
Brandts B, Bender K, Weismuller P, Pott L, Trappe H
Pacing Clin Electrophysiol . 2001 Jan; 23(11 Pt 2):1816-9. PMID: 11139932
ATP-sensitive K+ current (IK(ATP)) plays an important role in the regulation of cardiac electrical activity. In the myocardium, IK(ATP) is regulated by the sulfonylurea receptor (SURIIA) which mediates the inhibition...
9.
Brandts B, Van Bracht M, Tuttelmann F, Allessie M, Trappe H
Pacing Clin Electrophysiol . 2001 Jan; 23(11 Pt 2):1812-5. PMID: 11139931
RP58866 is a potent antiarrhythmic drug that maintains its antiarrhythmic properties during ischemia. Since interstitial concentrations of adenosine increase during ischemia, we examined the properties of the drug with respect...
10.
Weismuller P, Kattenbeck K, Brandts B, Trappe H
Internist (Berl) . 2000 Dec; 41(11):1247-52. PMID: 11127227
No abstract available.