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B A Parr

Explore the profile of B A Parr including associated specialties, affiliations and a list of published articles. Areas
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Citations 589
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Recent Articles
1.
Bikkavilli R, Avasarala S, Van Scoyk M, Arcaroli J, Brzezinski C, Zhang W, et al.
Oncogene . 2015 Oct; 34(42):5406. PMID: 26473947
No abstract available.
2.
Bikkavilli R, Avasarala S, Van Scoyk M, Arcaroli J, Brzezinski C, Zhang W, et al.
Oncogene . 2015 Mar; 34(42):5317-28. PMID: 25728679
Cellular senescence is an initial barrier for carcinogenesis. However, the signaling mechanisms that trigger cellular senescence are incompletely understood, particularly in vivo. Here we identify Wnt7a as a novel upstream...
3.
Parr B, Cornish V, Cybulsky M, McMahon A
Dev Biol . 2001 Sep; 237(2):324-32. PMID: 11543617
Secreted Wnt proteins regulate many developmental processes in multicellular organisms. We have generated a targeted mutation in the mouse Wnt7b gene. Homozygous Wnt7b mutant mice die at midgestation stages as...
4.
Carson C, Kinzler E, Parr B
Mech Dev . 2000 Aug; 96(1):137-40. PMID: 10940636
T-box genes encode transcription factors that regulate many developmental processes. We have cloned a novel mouse T-box gene, Tbx12. Tbx12 is the vertebrate homologue of the Drosophila H15 gene and...
5.
Parr B, McMahon A
Nature . 1998 Oct; 395(6703):707-10. PMID: 9790192
An important feature of mammalian development is the generation of sexually dimorphic reproductive tracts from the Müllerian and Wolffian ducts. In females, Müllerian ducts develop into the oviduct, uterus, cervix...
6.
Parr B, Avery E, Cygan J, McMahon A
Dev Biol . 1998 Oct; 202(2):228-34. PMID: 9769174
The study of spontaneous mutations has aided the understanding of developmental processes. A large collection of spontaneous or "classical" mouse mutations has been accumulated over many decades. One of the...
7.
Parr B, McMahon A
Nature . 1995 Mar; 374(6520):350-3. PMID: 7885472
Formation of the vertebrate limb requires specification of cell position along three axes. Proximal-distal identity is regulated by the apical ectodermal ridge (AER) at the distal tip of the growing...
8.
Parr B, McMahon A
Curr Opin Genet Dev . 1994 Aug; 4(4):523-8. PMID: 7950319
A variety of experimental approaches have underscored the critical role played by secreted polypeptide factors, such as those encoded by members of the Wnt gene family, in many aspects of...
9.
Parr B, Shea M, Vassileva G, McMahon A
Development . 1993 Sep; 119(1):247-61. PMID: 8275860
Mutation and expression studies have implicated the Wnt gene family in early developmental decision making in vertebrates and flies. In a detailed comparative analysis, we have used in situ hybridization...
10.
Parr B, Parks A, Raff R
J Biol Chem . 1990 Jan; 265(3):1408-13. PMID: 2295637
The early fate specification of primary mesenchyme cells in sea urchin embryos makes them an attractive system for studying alterations in gene expression and protein synthesis during cell lineage determination...