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B A Fiedel

Explore the profile of B A Fiedel including associated specialties, affiliations and a list of published articles. Areas
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1.
Potempa L, Zeller J, Fiedel B, Kinoshita C, Gewurz H
Inflammation . 1988 Aug; 12(4):391-405. PMID: 2459061
C-reactive protein (CRP) can be structurally modified by heat, acid, or urea-chelation to express a neoantigen designated by us as neo-CRP. This antigen is also expressed on the in vitro...
2.
Fiedel B
Immunology . 1988 Jul; 64(3):487-93. PMID: 3044982
C-reactive protein (CRP) is an acute-phase reactant that modifies platelet function differently, depending upon its physiochemical state. Aggregated and ligand-complexed forms of CRP initiate the activation of platelets, whereas naturally...
3.
Fiedel B
Immunology . 1988 Jan; 63(1):169-70. PMID: 3338818
Fibrinogen augmented gel-filtered platelet (GFP) aggregation only during an intermediate level of platelet activation stimulated by aggregated C-reactive protein (CRP) (AggCRP), implying that a mechanism to utilize fibrinogen is not...
4.
Potempa L, Siegel J, Fiedel B, Potempa R, Gewurz H
Mol Immunol . 1987 May; 24(5):531-41. PMID: 2443837
It has previously been reported that human C-reactive protein (CRP) can exist in at least two molecular conformations distinguished by antigenic, electrophoretic and ligand-binding reactivities. In the present study we...
5.
Fiedel B, Ku C
Thromb Haemost . 1986 Jun; 55(3):406-9. PMID: 3750270
Serum amyloid P component (SAP), and its acute phase homologue C-reactive protein (CRP), prolonged activated partial thromboplastin times (APTT) in cell free plasma when assayed at physiological concentrations in the...
6.
Fiedel B, Gewurz H
J Immunol . 1986 Apr; 136(7):2551-5. PMID: 2419439
C-reactive protein (CRP) is the prototypic acute phase reactant and serves clinically as a marker of inflammation and tissue destruction. When native CRP pentamer was incubated with Streptomyces griseus protease,...
7.
Fiedel B
Blood . 1985 Feb; 65(2):264-9. PMID: 2578299
C-reactive protein is the prototypic acute phase reactant. A self-complexed form (H-CRP) can induce isolated platelets to undergo aggregation, secretion of dense and alpha-granule constituents, and generation of thromboxane A2,...
8.
Fiedel B, Vallve C, Izzi J
Agents Actions . 1984 Jun; 14(5-6):738-42. PMID: 6475670
Rabbits made acute phase by sub-cutaneous trauma with 2% croton oil (in mineral oil) were tested by intradermal (ID) injection with platelet-granule extracts containing platelet-derived permeability factor (PDPF). Compared with...
9.
Ku C, Fiedel B
J Exp Med . 1983 Sep; 158(3):767-80. PMID: 6886628
Serum amyloid P-component (SAP) is a normal plasma constituent in man with a circulating concentration of approximately 40 micrograms/ml. Supraphysiological amounts of SAP (150-300 micrograms/ml) have been reported to affect...
10.
Fiedel B, Ku C, Izzi J, Gewurz H
J Immunol . 1983 Sep; 131(3):1416-9. PMID: 6886420
One component of amyloid, protein AP, has a characteristic pentameric structure and is identical with a 9.5s serum alpha 1-globulin designated serum amyloid P-component or SAP. Another pentameric molecule, the...