Axel Cournac
Overview
Explore the profile of Axel Cournac including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
23
Citations
1203
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Girard F, Even A, Thierry A, Ruault M, Meneu L, Larrous P, et al.
EMBO J
. 2025 Feb;
PMID: 40016420
Natural plasmids are common in prokaryotes, but few have been documented in eukaryotes. The natural 2µ plasmid present in the yeast Saccharomyces cerevisiae is one of these best-characterized exceptions. This...
2.
Bastie N, Chapard C, Cournac A, Nejmi S, Mboumba H, Gadal O, et al.
Mol Cell
. 2024 Mar;
84(6):1139-1148.e5.
PMID: 38452765
Eukaryotic genomes are folded into DNA loops mediated by structural maintenance of chromosomes (SMC) complexes such as cohesin, condensin, and Smc5/6. This organization regulates different DNA-related processes along the cell...
3.
Diogo Dias J, Sarica N, Cournac A, Koszul R, Neuveut C
Viruses
. 2022 Feb;
14(2).
PMID: 35216038
Viruses that transcribe their DNA within the nucleus have to adapt to the existing cellular mechanisms that govern transcriptional regulation. Recent technological breakthroughs have highlighted the highly hierarchical organization of...
4.
Matthey-Doret C, Baudry L, Mortaza S, Moreau P, Koszul R, Cournac A
Methods Mol Biol
. 2021 Aug;
2301:1-15.
PMID: 34415528
Over the last decade, genomic proximity ligation approaches have reshaped our vision of chromosomes 3D organizations, from bacteria nucleoids to larger eukaryotic genomes. The different protocols (3Cseq, Hi-C, TCC, MicroC...
5.
Matthey-Doret C, Baudry L, Breuer A, Montagne R, Guiglielmoni N, Scolari V, et al.
Nat Commun
. 2020 Nov;
11(1):5795.
PMID: 33199682
Chromosomes of all species studied so far display a variety of higher-order organisational features, such as self-interacting domains or loops. These structures, which are often associated to biological functions, form...
6.
Dauban L, Montagne R, Thierry A, Lazar-Stefanita L, Bastie N, Gadal O, et al.
Mol Cell
. 2020 Feb;
77(6):1279-1293.e4.
PMID: 32032532
Cohesin, a member of the SMC complex family, holds sister chromatids together but also shapes chromosomes by promoting the formation of long-range intra-chromatid loops, a process proposed to be mediated...
7.
Garcia-Luis J, Lazar-Stefanita L, Gutierrez-Escribano P, Thierry A, Cournac A, Garcia A, et al.
Nat Struct Mol Biol
. 2019 Oct;
26(10):970-979.
PMID: 31582854
Cohesin is a regulator of genome architecture with roles in sister chromatid cohesion and chromosome compaction. The recruitment and mobility of cohesin complexes on DNA is restricted by nucleosomes. Here,...
8.
Moreau P, Cournac A, Palumbo G, Marbouty M, Mortaza S, Thierry A, et al.
Nat Commun
. 2018 Oct;
9(1):4268.
PMID: 30323189
Whether non-integrated viral DNAs distribute randomly or target specific positions within the higher-order architecture of mammalian genomes remains largely unknown. Here we use Hi-C and viral DNA capture (CHi-C) in...
9.
Baudement M, Cournac A, Court F, Seveno M, Parrinello H, Reynes C, et al.
Genome Res
. 2018 Oct;
28(11):1733-1746.
PMID: 30287550
The mammalian cell nucleus contains numerous discrete suborganelles named nuclear bodies. While recruitment of specific genomic regions into these large ribonucleoprotein (RNP) complexes critically contributes to higher-order functional chromatin organization,...
10.
Lioy V, Cournac A, Marbouty M, Duigou S, Mozziconacci J, Espeli O, et al.
Cell
. 2018 Jan;
172(4):771-783.e18.
PMID: 29358050
As in eukaryotes, bacterial genomes are not randomly folded. Bacterial genetic information is generally carried on a circular chromosome with a single origin of replication from which two replication forks...