Aurelie H Benfield
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Explore the profile of Aurelie H Benfield including associated specialties, affiliations and a list of published articles.
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25
Citations
340
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Recent Articles
1.
Lamb H, Benfield A, Troeira Henriques S
Drug Discov Today
. 2024 Oct;
29(12):104206.
PMID: 39395530
Drug resistance is the leading cause of treatment failure in patients with cancer. Thus, innovative therapeutic strategies are required to overcome this critical challenge and improve patient outcomes. In this...
2.
Benfield A, Vernen F, Young R, Nadal-Bufi F, Lamb H, Hammerlindl H, et al.
Pharmacol Res
. 2024 Jul;
207:107298.
PMID: 39032840
Acquired drug resistance is the major cause for disease recurrence in cancer patients, and this is particularly true for patients with metastatic melanoma that carry a BRAF mutation. To address...
3.
Beccari G, Tini F, Foroud N, Ederli L, Gardiner D, Benfield A, et al.
BMC Plant Biol
. 2024 May;
24(1):463.
PMID: 38802782
Background: Fusarium graminearum and Fusarium avenaceum are two of the most important causal agents of Fusarium head blight (FHB) of wheat. They can produce mycotoxins that accumulate in infected wheat...
4.
Menzel J, Young R, Benfield A, Scott J, Wongsomboon P, Cudlman L, et al.
Nat Commun
. 2023 Jul;
14(1):3940.
PMID: 37402773
Fatty acid isomers are responsible for an under-reported lipidome diversity across all kingdoms of life. Isomers of unsaturated fatty acids are often masked in contemporary analysis by incomplete separation and...
5.
Wang C, Huang Y, Shabbir F, Pham H, Lawrence N, Benfield A, et al.
Peptides
. 2023 Jun;
167:171049.
PMID: 37390898
Bacteriocins are a large family of bacterial peptides that have antimicrobial activity and potential applications as clinical antibiotics or food preservatives. Circular bacteriocins are a unique class of these biomolecules...
6.
Benfield A, Troeira Henriques S
Front Med Technol
. 2022 Jan;
2:610997.
PMID: 35047892
Antimicrobial peptides are an attractive alternative to traditional antibiotics, due to their physicochemical properties, activity toward a broad spectrum of bacteria, and mode-of-actions distinct from those used by current antibiotics....
7.
Lawrence N, Philippe G, Harvey P, Condon N, Benfield A, Cheneval O, et al.
RSC Chem Biol
. 2021 Aug;
1(5):405-420.
PMID: 34458771
Cell penetrating peptides (CPPs) are valuable tools for developing anticancer therapies due to their ability to access intracellular targets, including protein-protein interactions. cPF4PD is a newly described CPP designed from...
8.
Gardiner D, Rusu A, Benfield A, Kazan K
Fungal Biol
. 2021 Feb;
125(3):191-200.
PMID: 33622535
Although better known as a pathogen of wheat stem bases, Fusarium pseudograminearum also causes Fusarium head blight. A natural isolate of F. pseudograminearum was identified that showed severely reduced virulence...
9.
Benfield A, Defaus S, Lawrence N, Chaousis S, Condon N, Cheneval O, et al.
Biochim Biophys Acta Biomembr
. 2020 Sep;
1863(1):183480.
PMID: 32979382
Anticancer chemo- and targeted therapies are limited in some cases due to strong side effects and/or drug resistance. Peptides have received renascent interest as anticancer therapeutics and are currently being...
10.
Peacock H, Troeira Henriques S, Benfield A, Elliott A, Luo J, Luccarelli J, et al.
ChemMedChem
. 2020 Aug;
15(20):1932-1939.
PMID: 32754982
Mimics of natural antimicrobial peptides are promising compounds to fight the rising threat of multi-drug resistant bacteria. Here we report the design, synthesis and conformational analysis of a new class...