Aundrea K Westfall
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Explore the profile of Aundrea K Westfall including associated specialties, affiliations and a list of published articles.
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12
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77
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Recent Articles
1.
Garg A, Xing C, Agarwal A, Westfall A, Tomchick D, Zhang X, et al.
Diabetes
. 2024 Dec;
74(3):427-438.
PMID: 39652711
Article Highlights: Molecular genetic defects in some ultra-rare subtypes of familial partial lipodystrophies (FPLs) remain unidentified. We investigated whether novel gene variants explain FPL in some undiagnosed patients. We found...
2.
Westfall A, Gopalan S, Kay J, Tippetts T, Cervantes M, Lackey K, et al.
Proc Natl Acad Sci U S A
. 2024 Oct;
121(43):e2405463121.
PMID: 39423244
Canonical models of intestinal regeneration emphasize the critical role of the crypt stem cell niche to generate enterocytes that migrate to villus ends. Burmese pythons possess extreme intestinal regenerative capacity...
3.
Westfall A, Gopalan S, Perry B, Adams R, Saviola A, Mackessy S, et al.
Genome Biol Evol
. 2023 Jun;
15(6).
PMID: 37311204
The ubiquitous cellular heterogeneity underlying many organism-level phenotypes raises questions about what factors drive this heterogeneity and how these complex heterogeneous systems evolve. Here, we use single-cell expression data from...
4.
Chamseddine D, Mahmud S, Westfall A, Castoe T, Berg R, Pellegrino M
Cell Rep
. 2022 Dec;
41(11):111789.
PMID: 36516750
Organisms use several strategies to mitigate mitochondrial stress, including the activation of the mitochondrial unfolded protein response (UPR). The UPR in Caenorhabditis elegans, regulated by the transcription factor ATFS-1, expands...
5.
Nikolakis Z, Schield D, Westfall A, Perry B, Ivey K, Orton R, et al.
Evolution
. 2022 Sep;
76(11):2513-2530.
PMID: 36111705
Hybrid zones provide valuable opportunities to understand the genomic mechanisms that promote speciation by providing insight into factors involved in intermediate stages of speciation. Here, we investigate introgression in a...
6.
Schield D, Perry B, Card D, Pasquesi G, Westfall A, Mackessy S, et al.
Genome Biol Evol
. 2022 Jul;
14(9).
PMID: 35867356
Sex chromosomes diverge after the establishment of recombination suppression, resulting in differential sex-linkage of genes involved in genetic sex determination and dimorphic traits. This process produces systems of male or...
7.
Perry B, Gopalan S, Pasquesi G, Schield D, Westfall A, Smith C, et al.
Genome Res
. 2022 Jun;
32(6):1058-1073.
PMID: 35649579
Understanding how regulatory mechanisms evolve is critical for understanding the processes that give rise to novel phenotypes. Snake venom systems represent a valuable and tractable model for testing hypotheses related...
8.
Westfall A, Perry B, Kamal A, Hales N, Kay J, Sapkota M, et al.
BMC Genomics
. 2022 Jan;
23(1):6.
PMID: 34983392
Background: Snakes exhibit extreme intestinal regeneration following months-long fasts that involves unparalleled increases in metabolism, function, and tissue growth, but the specific molecular control of this process is unknown. Understanding...
9.
Westfall A, Telemeco R, Grizante M, Waits D, Clark A, Simpson D, et al.
Gigascience
. 2021 Oct;
10(10).
PMID: 34599334
Background: High-quality genomic resources facilitate investigations into behavioral ecology, morphological and physiological adaptations, and the evolution of genomic architecture. Lizards in the genus Sceloporus have a long history as important...
10.
Perry B, Schield D, Westfall A, Mackessy S, Castoe T
Sci Rep
. 2020 Oct;
10(1):18083.
PMID: 33093509
Despite the extensive body of research on snake venom, many facets of snake venom systems, such as the physiology and regulation of the venom gland itself, remain virtually unstudied. Here,...