Aude de Gassart
Overview
Explore the profile of Aude de Gassart including associated specialties, affiliations and a list of published articles.
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Articles
29
Citations
1650
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Recent Articles
1.
Kerneur C, Foucher E, Guillen Casas J, Colazet M, Le K, Fullana M, et al.
Cell Rep
. 2024 Sep;
43(10):114773.
PMID: 39325623
Tumor-associated macrophages (TAMs), often adopting an immunosuppressive M2-like phenotype, correlate with unfavorable cancer outcomes. Our investigation unveiled elevated expression of the butyrophilin (BTN)2A1 in M2-like TAMs across diverse cancer types....
2.
Ribeiro S, de Gassart A, Bettigole S, Zaffalon L, Chavarria C, Op M, et al.
iScience
. 2022 Oct;
25(10):105227.
PMID: 36248746
DNA-damage inducible 1 homolog 2 (DDI2) is a protease that activates the transcription factor NRF1. Cellular models have shown that this pathway contributes to cell-stress adaptation, for example, on proteasome...
3.
Op M, Ribeiro S, Chavarria C, de Gassart A, Zaffalon L, Martinon F
Cell Death Dis
. 2022 May;
13(5):475.
PMID: 35589686
Proteasome inhibitors, such as bortezomib, are first-line therapy against multiple myeloma (MM). Unfortunately, patients frequently become refractory to this treatment. The transcription factor NRF1 has been proposed to initiate an...
4.
de Gassart A, Le K, Brune P, Agaugue S, Sims J, Goubard A, et al.
Sci Transl Med
. 2021 Oct;
13(616):eabj0835.
PMID: 34669444
Gamma delta T (γδ T) cells are among the most potent cytotoxic lymphocytes. Activating anti–butyrophilin 3A (BTN3A) antibodies prime diverse tumor cell types to be killed by Vγ9Vδ2 T cells,...
5.
Cano C, Pasero C, de Gassart A, Kerneur C, Gabriac M, Fullana M, et al.
Cell Rep
. 2021 Jul;
36(2):109359.
PMID: 34260935
The anti-tumor response of Vγ9Vδ2 T cells requires the sensing of accumulated phosphoantigens (pAgs) bound intracellularly to butyrophilin 3A1 (BTN3A1). In this study, we show that butyrophilin 2A1 (BTN2A1) is...
6.
De Angelis Rigotti F, de Gassart A, Pforr C, Cano F, Nguessan P, Combes A, et al.
Immunol Cell Biol
. 2017 Jun;
95(9):753-764.
PMID: 28559542
Given the heterogeneous nature of antigens, major histocompatibility complex class I (MHC I) intracellular transport intersects with multiple degradation pathways for efficient peptide loading and presentation to cytotoxic T cells....
7.
Bujisic B, de Gassart A, Tallant R, Demaria O, Zaffalon L, Chelbi S, et al.
Blood
. 2017 Feb;
129(17):2420-2428.
PMID: 28167662
The endoplasmic reticulum kinase inositol-requiring enzyme 1 (IRE1) and its downstream target X-box-binding protein 1 (XBP1) drive B-cell differentiation toward plasma cells and have been shown to contribute to multiple...
8.
de Gassart A, Martinon F
Cell Cycle
. 2016 Nov;
16(4):299-300.
PMID: 27830984
No abstract available.
9.
de Gassart A, Demaria O, Panes R, Zaffalon L, Ryazanov A, Gilliet M, et al.
EMBO Rep
. 2016 Aug;
17(10):1471-1484.
PMID: 27572820
Activation of the elongation factor 2 kinase (eEF2K) leads to the phosphorylation and inhibition of the elongation factor eEF2, reducing mRNA translation rates. Emerging evidence indicates that the regulation of...
10.
Di Micco A, Frera G, Lugrin J, Jamilloux Y, Hsu E, Tardivel A, et al.
Proc Natl Acad Sci U S A
. 2016 Jul;
113(32):E4671-80.
PMID: 27462105
Inflammasomes are critical sensors that convey cellular stress and pathogen presence to the immune system by activating inflammatory caspases and cytokines such as IL-1β. The nature of endogenous stress signals...