Atsushi Tsuchida
Overview
Explore the profile of Atsushi Tsuchida including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
2440
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Recent Articles
1.
Saito H, Kato M, Hirai K, Kiyama M, Ohyama K, Hanzawa H, et al.
J Biosci Bioeng
. 2021 Jul;
132(4):381-389.
PMID: 34284947
To improve cell production efficacy, it is important to evaluate cell conditions during culture. Extracellular vesicles (EVs) secreted from various cells are involved in stem cell differentiation. As EVs carry...
2.
Ushiroda K, Maruta K, Kitoh M, Iwai K, Nagamine J, Tsuchida A, et al.
Bioorg Med Chem Lett
. 2010 Dec;
21(1):220-4.
PMID: 21130649
Starting with a subtle blood glucose-lowering effect of a TGF-β inhibitor, we designed and synthesized a series of benzoylpyrrole-based carboxylic acids as PPARs activators. Among these compounds, 10sNa exhibited favorable...
3.
Takazawa T, Yamauchi T, Tsuchida A, Takata M, Hada Y, Iwabu M, et al.
J Biol Chem
. 2009 Aug;
284(44):30049-57.
PMID: 19706614
Apolipoprotein E (apoE) and its receptor, very low density lipoprotein receptor (VLDLR), are involved in fat accumulation in adipocytes. Here, we investigated the effect of a peroxisome proliferator-activated receptor (PPAR)...
4.
Yamanaka M, Itakura Y, Tsuchida A, Nakagawa T, Taiji M
Biomed Res
. 2008 Jul;
29(3):147-53.
PMID: 18614848
We previously reported that peripheral injection of brain-derived neurotrophic factor (BDNF) exhibits hypophagic and hypoglycemic effects in obese hyperglycemic animals, indicating its antiobesity and antidiabetic effects. Since previous studies were...
5.
Yamanaka M, Itakura Y, Ono-Kishino M, Tsuchida A, Nakagawa T, Taiji M
J Biosci Bioeng
. 2008 May;
105(4):395-402.
PMID: 18499057
We previously demonstrated that repetitive administration of brain-derived neurotrophic factor (BDNF) ameliorates glucose metabolism and energy expenditure in obese diabetic db/db mice. However, we have not evaluated in detail the...
6.
Kubota N, Yano W, Kubota T, Yamauchi T, Itoh S, Kumagai H, et al.
Cell Metab
. 2007 Jul;
6(1):55-68.
PMID: 17618856
Adiponectin has been shown to stimulate fatty acid oxidation and enhance insulin sensitivity through the activation of AMP-activated protein kinase (AMPK) in the peripheral tissues. The effects of adiponectin in...
7.
Hada Y, Yamauchi T, Waki H, Tsuchida A, Hara K, Yago H, et al.
Biochem Biophys Res Commun
. 2007 Mar;
356(2):487-93.
PMID: 17368570
Adiponectin is an adipocyte-derived hormone and known to form several species of multimer, however, the precise components of each multimer have not been fully determined. We purified each multimer adiponectin...
8.
Yamauchi T, Nio Y, Maki T, Kobayashi M, Takazawa T, Iwabu M, et al.
Nat Med
. 2007 Feb;
13(3):332-9.
PMID: 17268472
Adiponectin plays a central role as an antidiabetic and antiatherogenic adipokine. AdipoR1 and AdipoR2 serve as receptors for adiponectin in vitro, and their reduction in obesity seems to be correlated...
9.
Yamanaka M, Itakura Y, Inoue T, Tsuchida A, Nakagawa T, Noguchi H, et al.
Metabolism
. 2006 Sep;
55(10):1286-92.
PMID: 16979397
We have previously demonstrated that brain-derived neurotrophic factor (BDNF) ameliorates glucose metabolism and energy expenditure in obese diabetic db/db mice. In the present study, the effect of BDNF treatment on...
10.
Tsuchida A, Yamauchi T, Takekawa S, Hada Y, Ito Y, Maki T, et al.
Diabetes
. 2005 Nov;
54(12):3358-70.
PMID: 16306350
We examined the effects of activation of peroxisome proliferator-activated receptor (PPAR)alpha, PPARgamma, and both of them in combination in obese diabetic KKAy mice and investigated the mechanisms by which they...