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Atilla Kovacs

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Articles 7
Citations 293
Followers 0
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Recent Articles
1.
Amrute J, Luo X, Penna V, Yang S, Yamawaki T, Hayat S, et al.
Nature . 2024 Oct; 635(8038):423-433. PMID: 39443792
Inflammation and tissue fibrosis co-exist and are causally linked to organ dysfunction. However, the molecular mechanisms driving immune-fibroblast cell communication in human cardiac disease remain unexplored and there are at...
2.
Zhang H, Hanson A, Scherf de Almeida T, Emfinger C, McClenaghan C, Harter T, et al.
JCI Insight . 2021 Feb; 6(5). PMID: 33529173
Cantu syndrome (CS) is caused by gain-of-function (GOF) mutations in pore-forming (Kir6.1, KCNJ8) and accessory (SUR2, ABCC9) ATP-sensitive potassium (KATP) channel subunits, the most common mutations being SUR2[R1154Q] and SUR2[R1154W],...
3.
Levin M, Singh G, Zhang H, Uchida K, Kozel B, Stein P, et al.
Proc Natl Acad Sci U S A . 2016 Jun; 113(24):6773-8. PMID: 27247394
Cantu syndrome (CS) is caused by gain-of-function (GOF) mutations in genes encoding pore-forming (Kir6.1, KCNJ8) and accessory (SUR2, ABCC9) KATP channel subunits. We show that patients with CS, as well...
4.
Kovacs A, Budai A, Dobrossy L, Pentek Z, Ormandi K, Forrai G
Orv Hetil . 2010 Nov; 151(49):2031-2, discussion 2033-4.. PMID: 21106484
No abstract available.
5.
Woloszynek J, Kovacs A, Ohlemiller K, Roberts M, Sands M
J Biol Chem . 2009 Aug; 284(43):29684-91. PMID: 19700765
Lysosomal storage diseases (LSD) are metabolic disorders characterized by accumulation of undegraded material. The mucopolysaccharidoses (MPS) are LSDs defined by the storage of glycosaminoglycans. Previously, we hypothesized that cells affected...
6.
Huss J, Imahashi K, Dufour C, Weinheimer C, Courtois M, Kovacs A, et al.
Cell Metab . 2007 Jul; 6(1):25-37. PMID: 17618854
Downregulation and functional deactivation of the transcriptional coactivator PGC-1alpha has been implicated in heart failure pathogenesis. We hypothesized that the estrogen-related receptor alpha (ERRalpha), which recruits PGC-1alpha to metabolic target...
7.
Vega R, Rothermel B, Weinheimer C, Kovacs A, Naseem R, Bassel-Duby R, et al.
Proc Natl Acad Sci U S A . 2003 Jan; 100(2):669-74. PMID: 12515860
The calcium/calmodulin-dependent protein phosphatase calcineurin stimulates cardiac hypertrophy in response to numerous stimuli. Calcineurin activity is suppressed by association with modulatory calcineurin-interacting protein (MCIP)1DSCR1, which is up-regulated by calcineurin signaling...